Pathogenesis of viral infections during pregnancy
PS Creisher, SL Klein - Clinical Microbiology Reviews, 2024 - Am Soc Microbiol
Viral infections during pregnancy are associated with significant adverse perinatal and fetal
outcomes. Pregnancy is a unique immunologic and physiologic state, which can influence …
outcomes. Pregnancy is a unique immunologic and physiologic state, which can influence …
Transmission, seroprevalence, and maternal-fetal impact of lymphocytic choriomeningitis virus
NR Olivieri, L Othman, DD Flannery, SM Gordon - Pediatric Research, 2024 - nature.com
Congenital infections can have devastating short-and long-term impacts on the developing
fetus. Lymphocytic choriomeningitis virus (LCMV) is a zoonotic pathogen of concern that …
fetus. Lymphocytic choriomeningitis virus (LCMV) is a zoonotic pathogen of concern that …
Suppression of progesterone by influenza A virus mediates adverse maternal and fetal outcomes in mice
Influenza A virus infection during pregnancy can cause adverse maternal and fetal
outcomes but the mechanism responsible remains elusive. Infection of outbred mice with …
outcomes but the mechanism responsible remains elusive. Infection of outbred mice with …
Vitamin D modulates expression of antimicrobial peptides and proinflammatory cytokines to restrict Zika virus infection in macrophages
Although the impact of Zika virus (ZIKV) infection on human health has been well
documented, we still have no vaccine or effective treatment. This fact highlights the …
documented, we still have no vaccine or effective treatment. This fact highlights the …
Adverse outcomes in SARS-CoV-2–infected pregnant mice are gestational age–dependent and resolve with antiviral treatment
SARS-CoV-2 infection during pregnancy is associated with severe COVID-19 and adverse
fetal outcomes, but the underlying mechanisms remain poorly understood. Moreover, clinical …
fetal outcomes, but the underlying mechanisms remain poorly understood. Moreover, clinical …
Assessing the role of Ndel1 oligopeptidase activity in congenital Zika syndrome: Potential predictor of congenital syndrome endophenotype and treatment response
RR Christoff, JV Nani, G Lessa… - Journal of …, 2023 - Wiley Online Library
Maternal infections are among the main risk factors for cognitive impairments in the
offspring. Zika virus (ZIKV) can be transmitted vertically, causing a set of heterogeneous birth …
offspring. Zika virus (ZIKV) can be transmitted vertically, causing a set of heterogeneous birth …
Influenza subtype-specific maternal antibodies protect offspring against infection but inhibit vaccine-induced immunity and protection in mice
Following influenza A virus (IAV) infection or vaccination during pregnancy, maternal
antibodies are transferred to offspring in utero and during lactation. The age and sex of …
antibodies are transferred to offspring in utero and during lactation. The age and sex of …
Collateral Damage in the Placenta during Viral Infection in Pregnancy: A Possible Mechanism for Vertical Transmission and an Adverse Pregnancy Outcome
VJ Cruz-Holguín, LD González-García… - Diseases, 2024 - mdpi.com
In mammals, the placenta is a connection between a mother and a new developing
organism. This tissue has a protective function against some microorganisms, transports …
organism. This tissue has a protective function against some microorganisms, transports …
[HTML][HTML] Susceptibility and resilience to maternal immune activation are associated with differential expression of endogenous retroviral elements
F Herrero, FS Mueller, J Gruchot, P Küry… - Brain, Behavior, and …, 2023 - Elsevier
Endogenous retroviruses (ERVs) are ancestorial retroviral elements that were integrated
into the mammalian genome through germline infections and insertions during evolution …
into the mammalian genome through germline infections and insertions during evolution …
Sex-specific effect of antenatal Zika virus infection on murine fetal growth, placental nutrient transporters, and nutrient sensor signaling pathways
D Pereira-Carvalho, ACC Valim, CBV Andrade… - bioRxiv, 2023 - biorxiv.org
Maternal Zika virus (ZIKV) infection during pregnancy can associate with severe intrauterine
growth restriction (IUGR), placental damage, and metabolism disturbance, as well as …
growth restriction (IUGR), placental damage, and metabolism disturbance, as well as …