Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …

Tissue-resident memory T (Trm) cells constitute a recently identified lymphocyte lineage that
occupies tissues without recirculating. They provide a first response against infections …

T cell migration is essential for T cell responses; it allows for the detection of cognate antigen
at the surface of antigen-presenting cells and for interactions with other cells involved in the …

Maintenance of homeostatic immune surveillance and development of effective adaptive
immune responses require precise regulation of spatial and temporal lymphocyte trafficking …

INTRODUCTION Influenza virus infects the epithelial cells that line the respiratory tract.
Therefore, cytotoxic CD8+ T cells must traffic to this site to eliminate infected cells. The …

Cell migration is central to a multitude of physiological processes, including embryonic
development, immune surveillance, and wound healing, and deregulated migration is key to …

The phagocytic clearance of dying cells in a tissue is a highly orchestrated series of
intercellular events coordinated by a complex signaling network. Recent data from genetic …

The lymphatic vasculature is not considered a formal part of the immune system, but it is
critical to immunity. One of its major roles is in the coordination of the trafficking of antigen …

Glioblastoma (GBM) is the most lethal primary adult brain tumor and its pathology is
hallmarked by distorted neovascularization, diffuse tumor-associated macrophage …

Vedolizumab is a novel therapeutic monoclonal antibody recently approved for the treatment
of moderately to severely active ulcerative colitis and Crohn's disease in adults who have …