[HTML][HTML] Challenges and opportunities in modelling wet granulation in pharmaceutical industry–a critical review
Wet granulation is a key step in the pharmaceutical manufacturing of solid-dosage forms.
Wet granulation is used in pharmaceutical production to enhance formulation qualities such …
Wet granulation is used in pharmaceutical production to enhance formulation qualities such …
Continuous manufacturing in pharmaceutical process development and manufacturing
CL Burcham, AJ Florence… - Annual review of …, 2018 - annualreviews.org
The pharmaceutical industry has found new applications for the use of continuous
processing for the manufacture of new therapies currently in development. The …
processing for the manufacture of new therapies currently in development. The …
A comprehensive review on process and engineering aspects of pharmaceutical wet granulation
P Suresh, I Sreedhar, R Vaidhiswaran… - Chemical Engineering …, 2017 - Elsevier
Wet granulation is a very important unit operation that finds applications in many industries
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …
[图书][B] Continuous manufacturing of pharmaceuticals
P Kleinebudde, J Khinast, J Rantanen - 2017 - books.google.com
A comprehensive look at existing technologies and processes for continuous manufacturing
of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical …
of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical …
Microcrystalline cellulose, lactose and lignin blends: Process mapping of dry granulation via roll compaction
M Pishnamazi, S Casilagan, C Clancy, S Shirazian… - Powder Technology, 2019 - Elsevier
In this study, a process map was developed in an effort to improve the understanding of dry
granulation of pharmaceutical excipients by roll compaction process, and to implement the …
granulation of pharmaceutical excipients by roll compaction process, and to implement the …
DEM analysis of residence time distribution during twin screw granulation
C Zheng, L Zhang, N Govender, CY Wu - Powder technology, 2021 - Elsevier
Twin screw granulation (TSG) is increasingly used to produce granules in various industries,
such as food, pharmaceutical, and fine chemicals. However, there is a large parametric …
such as food, pharmaceutical, and fine chemicals. However, there is a large parametric …
Twin-screw granulation: Mechanistic understanding of the effect of material properties on key granule quality attributes through the analysis of mixing dynamics and …
This study focuses on understanding the effect of material properties on granule quality
attributes through the analysis of mixing dynamics and granulation rate mechanisms …
attributes through the analysis of mixing dynamics and granulation rate mechanisms …
Optimization of critical quality attributes in continuous twin-screw wet granulation via design space validated with pilot scale experimental data
H Liu, SC Galbraith, B Ricart, C Stanton… - International Journal of …, 2017 - Elsevier
In this study, the influence of key process variables (screw speed, throughput and liquid to
solid (L/S) ratio) of a continuous twin screw wet granulation (TSWG) was investigated using …
solid (L/S) ratio) of a continuous twin screw wet granulation (TSWG) was investigated using …
Comparison of scale-up strategies in twin-screw wet granulation
M Franke, T Riedel, R Meier, C Schmidt… - International Journal of …, 2023 - Elsevier
The aim of this study was to compare different scale-up strategies in twin-screw wet
granulation and investigate the impact of the selected strategy on granule and tablet …
granulation and investigate the impact of the selected strategy on granule and tablet …
A review of regime maps for granulation
S Pohl, P Kleinebudde - International Journal of Pharmaceutics, 2020 - Elsevier
Granulation, a size enlargement technique to form agglomerates of primary particles, has
proven to be effective in the production of solid dosage forms. Numerous granulation …
proven to be effective in the production of solid dosage forms. Numerous granulation …