[HTML][HTML] Polymeric particle-based therapies for acute inflammatory diseases

ER Brannon, MV Guevara, NJ Pacifici, JK Lee… - Nature Reviews …, 2022 - nature.com
Acute inflammation is essential for initiating and coordinating the body's response to injuries
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …

[HTML][HTML] Nanomedicine for acute respiratory distress syndrome: the latest application, targeting strategy, and rational design

Q Qiao, X Liu, T Yang, K Cui, L Kong, C Yang… - … Pharmaceutica Sinica B, 2021 - Elsevier
Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation
and destruction of the lung air–blood barrier, leading to irreversible and substantial …

[HTML][HTML] CAR-neutrophil mediated delivery of tumor-microenvironment responsive nanodrugs for glioblastoma chemo-immunotherapy

Y Chang, X Cai, R Syahirah, Y Yao, Y Xu, G Jin… - Nature …, 2023 - nature.com
Glioblastoma (GBM) is one of the most aggressive and lethal solid tumors in human. While
efficacious therapeutics, such as emerging chimeric antigen receptor (CAR)-T cells and …

An inhalable hybrid biomimetic nanoplatform for sequential drug release and remodeling lung immune homeostasis in acute lung injury treatment

C Liu, L Xi, Y Liu, JCW Mak, S Mao, Z Wang, Y Zheng - ACS nano, 2023 - ACS Publications
Interactions of lung macrophages and recruited neutrophils with the lung microenvironment
continuously aggravate the dysregulation of lung inflammation in the pathogenesis of acute …

Non-spherical micro-and nanoparticles for drug delivery: Progress over 15 years

N Kapate, JR Clegg, S Mitragotri - Advanced Drug Delivery Reviews, 2021 - Elsevier
Shape of particulate drug carries has been identified as a key parameter in determining their
biological outcome. In this review, we analyze the field of particle shape as it shifts from …

Immunomodulatory biomaterials and their application in therapies for chronic inflammation-related diseases

JR Nakkala, Z Li, W Ahmad, K Wang, C Gao - Acta Biomaterialia, 2021 - Elsevier
The degree of tissue injuries such as the level of scarring or organ dysfunction, and the
immune response against them primarily determine the outcome and speed of healing …

Shape transformable strategies for drug delivery

W Jia, Y Wang, R Liu, X Yu… - Advanced Functional …, 2021 - Wiley Online Library
In tumor therapy, nanodrug delivery systems have gained momentum in the last decade.
However, its efficacy remains insufficient for clinical applications. The physical properties of …

[HTML][HTML] Neutrophils and macrophages as targets for development of nanotherapeutics in inflammatory diseases

Y Su, J Gao, P Kaur, Z Wang - Pharmaceutics, 2020 - mdpi.com
Neutrophils and macrophages are major components of innate systems, playing central
roles in inflammation responses to infections and tissue injury. If they are out of control …

Transition metal‐based therapies for inflammatory diseases

Y Song, Q You, X Chen - Advanced Materials, 2023 - Wiley Online Library
Inflammatory disease (ID) is a general term that covers all diseases in which chronic
inflammation performs as the major manifestation of pathogenesis. Traditional therapies …

Immunomodulatory nanosystems for treating inflammatory diseases

N Ahamad, A Kar, S Mehta, M Dewani, V Ravichandran… - Biomaterials, 2021 - Elsevier
Inflammatory disease (ID) is an umbrella term encompassing all illnesses involving chronic
inflammation as the central manifestation of pathogenesis. These include, inflammatory …