Impaired NFAT and NFκB activation are involved in suppression of CD40 ligand expression by Δ9-tetrahydrocannabinol in human CD4+ T cells

T Ngaotepprutaram, BLF Kaplan… - Toxicology and applied …, 2013 - Elsevier
We have previously reported that Δ 9-tetrahydrocannabinol (Δ 9-THC), the main
psychoactive cannabinoid in marijuana, suppresses CD40 ligand (CD40L) expression by …

A T-cell-specific CD154 transcriptional enhancer located just upstream of the promoter

M Brunner, M Zhang, A Genin, IC Ho, RQ Cron - Genes & Immunity, 2008 - nature.com
Abstract CD154 (CD40-ligand) is a critical immune regulator. CD154 expression is tightly
regulated and largely restricted to activated CD4 T cells. Using DNase I hypersensitivity site …

[图书][B] The molecular regulation of CD40L in CD8+ T cells

LG Loyal - 2019 - search.proquest.com
T Zellen können in zwei Hauptpopulationen mit unterschiedlichen Aufgaben unterschieden
werden. CD4+ T Zellen exprimieren im Zuge ihrer Aktivierung CD40L, welches ein zentraler …