Roles of long non-coding RNAs in angiogenesis-related diseases: Focusing on non-neoplastic aspects

D Li, L Liu, X He, N Wang, R Sun, X Li, T Yu, X Chu - Life sciences, 2023 - Elsevier
Angiogenesis is a key process in organ and tissue morphogenesis, as well as growth during
human development, and is coordinated by pro-and anti-angiogenic factors. When this …

LncRNAs and CircRNAs as Strategies against Pathological Conditions Caused by a Hypoxic/Anoxic State

I Anchesi, G Schepici, E Mazzon - Biomolecules, 2023 - mdpi.com
Brain damage can be induced by oxygen deprivation. It is known that hypoxic or anoxic
conditions can lead to changes in the expression levels of non-coding RNAs (ncRNAs) …

The evolving role of long noncoding RNA HIF1A-AS2 in diabetic retinopathy: a cross-link axis between hypoxia, oxidative stress and angiogenesis via MAPK/VEGF …

MM Atef, NM Shafik, YM Hafez, MM Watany… - Redox …, 2022 - Taylor & Francis
Background Diabetic retinopathy (DR) signifies a frequent serious diabetic complication
influencing retinal structure and function. Dysregulation of lncRNAs drives a wide array of …

Association of LncRNA-PAX8-AS1 and LAIR-2 polymorphisms along with their expression with clinical and subclinical hypothyroidism

OM Elsayed, SA Abdelazim, HA Darwish, OG Shaker… - Scientific Reports, 2023 - nature.com
The genetic and epigenetic architecture of clinical and subclinical hypothyroidism remains
unclear. We investigated the impact of long noncoding RNA (LncRNA)-PAX8-AS1 and LAIR …

Multi-level biomarkers for early Diagnosis of Ischaemic stroke: a systematic review and meta-analysis

Q Li, L Zhao, CL Chan, Y Zhang, SW Tong… - International journal of …, 2023 - mdpi.com
Blood biomarkers hold potential for the early diagnosis of ischaemic stroke (IS). We aimed to
evaluate the current weight of evidence and identify potential biomarkers and biological …

Altered lnc-EGFR, SNHG1, and LincRNA-cox2 profiles in patients with relapsing-remitting multiple sclerosis: impact on disease activity and progression

MS Attia, HA Ewida, MA Abdel Hafez, SA El-Maraghy… - Diagnostics, 2023 - mdpi.com
Relapsing–remitting multiple sclerosis (RRMS) is the most prevalent MS subtype. Ample
evidence has indicated that long noncoding RNAs (lncRNAs) are crucial players in …

Electroacupuncture enhances cerebral blood perfusion by inhibiting HIF-1α in rat subarachnoid hemorrhage

Y Wang, Y Chen, Z Li, L Tang, D Wen, Y Wu, Z Guo - Brain Research, 2024 - Elsevier
Objective Cerebral blood perfusion (CBP) reduction is a prevalent complication following
subarachnoid hemorrhage (SAH) in clinical practice, often associated with long-term …

Uncovering the mechanism of Chuanhong stroke capsule in the treatment of stroke based on network pharmacology and molecular docking technology

X Wang, D Zhao, JM Kan, J Wang… - Natural Product …, 2022 - journals.sagepub.com
Background and Objective: Chuanhong Stroke Capsule (CHSC) has good clinical efficacy in
the treatment of cerebral ischemic stroke (CIS) patients. This study aimed to investigate the …

Key lncRNAs involved in ischemic strokes

A Tuttolomondo, A Pinto - Epigenomics, 2022 - Taylor & Francis
Many RNA transcripts can be classified as noncoding RNA (ncRNA), suggesting their role
as pleiotropic potential effectors in the pathogenetic pathways of several diseases, such as …