Fetal alcohol spectrum disorders and abnormal neuronal plasticity

AE Medina - The Neuroscientist, 2011 - journals.sagepub.com
The ingestion of alcohol during pregnancy can result in a group of neurobehavioral
abnormalities collectively known as fetal alcohol spectrum disorders (FASD). During the past …

Neurotrophins in the brain: interaction with alcohol exposure during development

KE Boschen, AY Klintsova - Vitamins and hormones, 2017 - Elsevier
Fetal alcohol spectrum disorders (FASDs) are a result of the teratogenic effects of alcohol on
the developing fetus. Decades of research examining both individuals with FASDs and …

Persistent impairment of hippocampal neurogenesis in young adult rats following early postnatal alcohol exposure

AY Klintsova, JL Helfer, LH Calizo… - Alcoholism: Clinical …, 2007 - Wiley Online Library
Background: Prenatal alcohol exposure can cause damage to the developing fetus with
outcomes including growth deficiency, facial dysmorphology, brain damage, and cognitive …

Prenatal alcohol exposure reduces the proportion of newly produced neurons and glia in the dentate gyrus of the hippocampus in female rats

KA Uban, JH Sliwowska, S Lieblich, LA Ellis… - Hormones and …, 2010 - Elsevier
Prenatal alcohol exposure (PAE) alters adult neurogenesis and the neurogenic response to
stress in male rats. As the effects of stress on neurogenesis are sexually dimorphic, the …

[HTML][HTML] A randomized controlled trial of transcranial direct-current stimulation and cognitive training in children with fetal alcohol spectrum disorder

E Boroda, AM Krueger, P Bansal, MJ Schumacher… - Brain stimulation, 2020 - Elsevier
Background This study was a randomized double-blind sham-controlled trial examining the
effects of transcranial direct current stimulation (tDCS) augmented cognitive training (CT) in …

Effects of one-and three-day binge alcohol exposure in neonatal C57BL/6 mice on spatial learning and memory in adolescence and adulthood

JL Wagner, FC Zhou, CR Goodlett - Alcohol, 2014 - Elsevier
Binge-like alcohol exposure during the early postnatal period in rats and mice causes
deficits in spatial learning and memory that persist into adulthood. Wozniak et al.(2004) …

Deficits in trace fear conditioning in a rat model of fetal alcohol exposure: dose–response and timing effects

PS Hunt, SE Jacobson, EJ Torok - Alcohol, 2009 - Elsevier
In humans, prenatal alcohol exposure can result in significant impairments in several types
of learning and memory, including declarative and spatial memory. Animal models have …

Phosphodiesterase type 1 inhibition improves learning in rats exposed to alcohol during the third trimester equivalent of human gestation

CC Filgueiras, TE Krahe, AE Medina - Neuroscience letters, 2010 - Elsevier
Deficits in learning and memory have been extensively observed in animal models of fetal
alcohol spectrum disorders (FASD). Here we use the Morris maze to test whether …

Neonatal alcohol exposure and the hippocampus in developing male rats: effects on behaviorally induced CA1 c-Fos expression, CA1 pyramidal cell number, and …

NJ Murawski, AY Klintsova, ME Stanton - Neuroscience, 2012 - Elsevier
Rats exposed to a high binge-like dose of alcohol over postnatal days (PD) 4–9 show
reductions in CA1 pyramidal cells and impairments on behavioral tasks that depend on the …

Deconstructing the function of maternal stimulation in offspring development: Insights from the artificial rearing model in rats

AM Lomanowska, AI Melo - Hormones and Behavior, 2016 - Elsevier
This article is part of a Special Issue on “Parental Care”. Maternal behavior has an important
function in stimulating adequate growth and development of the young. Several approaches …