Mannich bases in medicinal chemistry and drug design
G Roman - European journal of medicinal chemistry, 2015 - Elsevier
The biological activity of Mannich bases, a structurally heterogeneous class of chemical
compounds that are generated from various substrates through the introduction of an …
compounds that are generated from various substrates through the introduction of an …
Pharmacological significance of triazole scaffold
The triazole nucleus is one of the most important and well known heterocycles which is a
common and integral feature of a variety of natural products and medicinal agents. Triazole …
common and integral feature of a variety of natural products and medicinal agents. Triazole …
New pyrazole derivatives containing 1, 2, 4-triazoles and benzoxazoles as potent antimicrobial and analgesic agents
Azole class of compounds are well known for their excellent therapeutic properties. Present
paper describes about the synthesis of three series of new 1, 2, 4-triazole and benzoxazole …
paper describes about the synthesis of three series of new 1, 2, 4-triazole and benzoxazole …
[HTML][HTML] Biological activities of Schiff bases and their complexes: a review of recent works
W Al Zoubi - International Journal of Organic Chemistry, 2013 - scirp.org
Schiff bases are the most widely used organic compounds. They have been shown to exhibit
a broad range of biological activities, including antifungal, antibacterial, antimalarial …
a broad range of biological activities, including antifungal, antibacterial, antimalarial …
Recent developments in azole compounds as antibacterial and antifungal agents
XM Peng, GX Cai, CH Zhou - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Azole compounds are an important class of nitrogen heterocycles with electron-rich
property. This special structure endows azole-based derivatives easily bind with the …
property. This special structure endows azole-based derivatives easily bind with the …
[HTML][HTML] Schiff's bases of quinazolinone derivatives: Synthesis and SAR studies of a novel series of potential anti-inflammatory and antioxidants
KP Rakesh, HM Manukumar, DC Gowda - Bioorganic & medicinal …, 2015 - Elsevier
A series of quinazolinone derived Schiff base derivatives 7–28 were synthesized and
characterized as novel antioxidants and anti-inflammatory agents. The in vitro antioxidant …
characterized as novel antioxidants and anti-inflammatory agents. The in vitro antioxidant …
Metal incorporated sulfonamides as promising multidrug targets: Combined enzyme inhibitory, antimicrobial, antioxidant and theoretical exploration
In this report, new sulfonamide based ligands (L 1)-(L 3) from 4-amino-N-(pyrimidin-2-yl)
benzene-1-sulfonamide are synthesized and branded on the basis of their physical …
benzene-1-sulfonamide are synthesized and branded on the basis of their physical …
[HTML][HTML] Molecular docking studies of some new imidazole derivatives for antimicrobial properties
In modern drug designing, molecular docking is routinely used for understanding drug-
receptor interaction. In the present study six imidazole derivatives containing substituted …
receptor interaction. In the present study six imidazole derivatives containing substituted …
Hantzsch reaction: synthesis and characterization of some new 1, 4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents
In the present study two new series of Hantzsch 1, 4-dihydropyridine derivatives (1, 4-DHPs)
containing substituted pyrazole moiety (4a–f and 5a–f) were synthesized by the reaction of 3 …
containing substituted pyrazole moiety (4a–f and 5a–f) were synthesized by the reaction of 3 …
Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives
In the present study two series of novel imidazole derivatives containing substituted pyrazole
moiety (3a–d and 5a–j) were synthesized. The first series were synthesized by the reaction …
moiety (3a–d and 5a–j) were synthesized. The first series were synthesized by the reaction …