Microbiome-based therapeutics
MT Sorbara, EG Pamer - Nature Reviews Microbiology, 2022 - nature.com
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
Obesity: epidemiology, pathophysiology, and therapeutics
X Lin, H Li - Frontiers in endocrinology, 2021 - frontiersin.org
Obesity is a complex multifactorial disease that accumulated excess body fat leads to
negative effects on health. Obesity continues to accelerate resulting in an unprecedented …
negative effects on health. Obesity continues to accelerate resulting in an unprecedented …
Gut microbiota-derived metabolites as central regulators in metabolic disorders
Metabolic disorders represent a growing worldwide health challenge due to their
dramatically increasing prevalence. The gut microbiota is a crucial actor that can interact …
dramatically increasing prevalence. The gut microbiota is a crucial actor that can interact …
The gut microbiota in obesity and weight management: microbes as friends or foe?
Obesity is caused by a long-term difference between energy intake and expenditure—an
imbalance that is seemingly easily restored by increasing exercise and reducing caloric …
imbalance that is seemingly easily restored by increasing exercise and reducing caloric …
The critical role of gut microbiota in obesity
Z Cheng, L Zhang, L Yang, H Chu - Frontiers in endocrinology, 2022 - frontiersin.org
Obesity is a global epidemic characterized by energy disequilibrium, metabolic disorder, fat
mass development, and chronic low-grade inflammation, which significantly affects the …
mass development, and chronic low-grade inflammation, which significantly affects the …
Safety and efficacy of fecal microbiota transplantation for treatment of systemic lupus erythematosus: An EXPLORER trial
C Huang, P Yi, M Zhu, W Zhou, B Zhang, X Yi… - Journal of …, 2022 - Elsevier
Gut microbiota dysbiosis is involved in the development of systemic lupus erythematosus
(SLE). The safety and efficacy of fecal microbiota transplantation (FMT) for the treatment of …
(SLE). The safety and efficacy of fecal microbiota transplantation (FMT) for the treatment of …
Gut liver brain axis in diseases: the implications for therapeutic interventions
M Yan, S Man, B Sun, L Ma, L Guo, L Huang… - Signal Transduction and …, 2023 - nature.com
Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …
Microbiota and fatty liver disease—the known, the unknown, and the future
S Lang, B Schnabl - Cell host & microbe, 2020 - cell.com
The liver communicates with the intestine via the portal vein, biliary system, and mediators in
the circulation. Microbes in the intestine maintain liver homeostasis but can also serve as a …
the circulation. Microbes in the intestine maintain liver homeostasis but can also serve as a …
Fecal microbiota transplantation in human metabolic diseases: from a murky past to a bright future?
NMJ Hanssen, WM de Vos, M Nieuwdorp - Cell metabolism, 2021 - cell.com
Fecal microbiota transplantation (FMT) is gaining considerable traction as a therapeutic
approach to influence the course of a plethora of chronic conditions, ranging from metabolic …
approach to influence the course of a plethora of chronic conditions, ranging from metabolic …
Microbiota engraftment after faecal microbiota transplantation in obese subjects with type 2 diabetes: a 24-week, double-blind, randomised controlled trial
Objective The impact of faecal microbiota transplantation (FMT) on microbiota engraftment in
patients with metabolic syndrome is uncertain. We aimed to study whether combining FMT …
patients with metabolic syndrome is uncertain. We aimed to study whether combining FMT …