Safety of 80 antidepressants, antipsychotics, anti‐attention‐deficit/hyperactivity medications and mood stabilizers in children and adolescents with psychiatric …

M Solmi, M Fornaro, EG Ostinelli, C Zangani… - World …, 2020 - Wiley Online Library
Mental disorders frequently begin in childhood or adolescence. Psychotropic medications
have various indications for the treatment of mental disorders in this age group and are used …

[HTML][HTML] Bipolar depression: a review of treatment options

K Levenberg, ZA Cordner - General Psychiatry, 2022 - ncbi.nlm.nih.gov
Bipolar depression (BD-D) is both common and incredibly challenging to treat. Even treated
individuals with BD-D experience depression approximately 19% of the time, and …

Multi-target approach for drug discovery against schizophrenia

M Kondej, P Stępnicki, AA Kaczor - International journal of molecular …, 2018 - mdpi.com
Polypharmacology is nowadays considered an increasingly crucial aspect in discovering
new drugs as a number of original single-target drugs have been performing far behind …

Application of antipsychotic drugs in mood disorders

JK Rybakowski - Brain Sciences, 2023 - mdpi.com
Since their first application in psychiatry seventy years ago, antipsychotic drugs, besides
schizophrenia, have been widely used in the treatment of mood disorders. Such an …

Exploring micellar-based polymeric systems for effective nose-to-brain drug delivery as potential neurotherapeutics

V Pokharkar, S Suryawanshi… - Drug Delivery and …, 2020 - Springer
Non-invasive nose-to-brain delivery presents a competitive strategy for effective drug
targeting. This strategy can potentially evade the blood-brain barrier (BBB) depending on …

Mood stabilizers of first and second generation

JK Rybakowski - Brain Sciences, 2023 - mdpi.com
The topic of this narrative review is mood stabilizers. First, the author's definition of mood-
stabilizing drugs is provided. Second, mood-stabilizing drugs meeting this definition that …

Risk factors, prevention and treatment of weight gain associated with the use of antidepressants and antipsychotics: a state-of-the-art clinical review

M Solmi, A Miola, F Capone, S Pallottino… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction People with severe mental illness have poor cardiometabolic health. Commonly
used antidepressants and antipsychotics frequently lead to weight gain, which may further …

Robust analytical method for the enantiomeric separation of lurasidone hydrochloride: Integrating analytical quality by design and green chemistry principles

MA Babaker, AM Algohary, AM Ibrahim - Sustainable Chemistry and …, 2024 - Elsevier
Schizophrenia, affecting approximately 1% of the global population, necessitates effective
treatments like Lurasidone (LUR). However, the accurate separation of LUR from its …

New investigational agents for the treatment of major depressive disorder

B Pochwat, AJ Krupa, M Siwek… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Pharmacotherapy of depression is characterized by the delayed onset of action,
chronic treatment requirements, and insufficient effectiveness. Ketamine, with its rapid action …

Improving Quality of Life in Bipolar Disorders with an Immersive Virtual Reality Remediation Training Randomized Controlled Trial (RCT)

D Primavera, GM Migliaccio, V Garau, G Orrù… - Journal of Clinical …, 2024 - mdpi.com
Background: Health-related quality of life (H-QoL) is a critical measure in bipolar disorder
(BD). Recent trials using virtual reality (VR) have shown potential in improving H-QoL …