Extracellular vesicles are membrane-bound vesicles containing proteins, lipids, RNAs and
microRNAs. They can originate from both healthy and stressed cells, and provide a …

Alcoholic liver disease is the result of cascade events, which clinically first lead to alcoholic
fatty liver, and then mostly via alcoholic steatohepatitis or alcoholic hepatitis potentially to …

Endoplasmic reticulum (ER) stress promotes tumor cell escape from immunosurveillance.
However, the underlying mechanisms remain unknown. We hypothesized that ER stress …

Circulating biomarkers have a great potential in diagnosing cancer diseases at early stages,
where curative treatment is a realistic possibility. In the recent years, using extracellular …

Fructose intake is known to induce obesity, insulin resistance, metabolic syndrome, and
nonalcoholic fatty liver disease (NAFLD). We aimed to evaluate the effects of fructose …

Alcoholism is a widespread and damaging behaviour of people throughout the world. Long-
term alcohol consumption has resulted in alcoholic liver disease (ALD) being the leading …

The Alcohol Use Disorders Identification Test (AUDIT) and its short form, the AUDIT-C, the
main clinical instruments used to identify unhealthy drinking behaviors, are influenced by …

Background and Aims Mitochondrial double‐stranded RNA (mtdsRNA) and its innate
immune responses have been reported previously; however, mtdsRNA generation and its …

Background & Aims Liver sinusoidal endothelial cell (LSEC) dysfunction has been reported
in alcohol-related liver disease, yet it is not known whether LSECs metabolize alcohol. Thus …

Excessive alcohol consumption is a global healthcare problem with enormous social,
economic, and clinical consequences. While chronic, heavy alcohol consumption causes …