Understanding the diversity of membrane lipid composition

T Harayama, H Riezman - Nature reviews Molecular cell biology, 2018 - nature.com
Cellular membranes are formed from a chemically diverse set of lipids present in various
amounts and proportions. A high lipid diversity is universal in eukaryotes and is seen from …

Lipid transfer proteins: the lipid commute via shuttles, bridges and tubes

LH Wong, AT Gatta, TP Levine - Nature reviews Molecular cell biology, 2019 - nature.com
Lipids are distributed in a highly heterogeneous fashion in different cellular membranes.
Only a minority of lipids achieve their final intracellular distribution through transport by …

Mammalian lipids: structure, synthesis and function

S Cockcroft - Essays in biochemistry, 2021 - portlandpress.com
Lipids are essential constituents of cellular membranes. Once regarded merely as structural
components, lipids have taken centre stage with the discovery of their roles in cell signalling …

Mechanisms of nonvesicular lipid transport

KM Reinisch, WA Prinz - Journal of Cell Biology, 2021 - rupress.org
We have long known that lipids traffic between cellular membranes via vesicles but have
only recently appreciated the role of nonvesicular lipid transport. Nonvesicular transport can …

[HTML][HTML] Insights into VPS13 properties and function reveal a new mechanism of eukaryotic lipid transport

M Leonzino, KM Reinisch, P De Camilli - Biochimica et Biophysica Acta …, 2021 - Elsevier
The occurrence of protein mediated lipid transfer between intracellular membranes has
been known since the late 1960's. Since these early discoveries, numerous proteins …

Kingdom Chromista and its eight phyla: a new synthesis emphasising periplastid protein targeting, cytoskeletal and periplastid evolution, and ancient divergences

T Cavalier-Smith - Protoplasma, 2018 - Springer
In 1981 I established kingdom Chromista, distinguished from Plantae because of its more
complex chloroplast-associated membrane topology and rigid tubular multipartite ciliary …

Advances on the transfer of lipids by lipid transfer proteins

LH Wong, A Čopič, TP Levine - Trends in biochemical sciences, 2017 - cell.com
Transfer of lipid across the cytoplasm is an essential process for intracellular lipid traffic.
Lipid transfer proteins (LTPs) are defined by highly controlled in vitro experiments. The …

Sequence analysis and structural predictions of lipid transfer bridges in the repeating beta groove (RBG) superfamily reveal past and present domain variations …

TP Levine - Contact, 2022 - journals.sagepub.com
Lipid transfer between organelles requires proteins that shield the hydrophobic portions of
lipids as they cross the cytoplasm. In the last decade a new structural form of lipid transfer …

Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites

T Di Mattia, LP Wilhelm, S Ikhlef, C Wendling… - EMBO …, 2018 - embopress.org
Membrane contact sites are cellular structures that mediate interorganelle exchange and
communication. The two major tether proteins of the endoplasmic reticulum (ER), VAP‐A …

Vitamin E: regulatory role on signal transduction

JM Zingg - IUBMB life, 2019 - Wiley Online Library
Vitamin E modulates signal transduction pathways by several molecular mechanisms. As a
hydrophobic molecule located mainly in membranes it contributes together with other lipids …