Dilated cardiomyopathy (DCM) is a clinical diagnosis characterized by left ventricular or
biventricular dilation and impaired contraction that is not explained by abnormal loading …

Abstract The Suppression of Tumorigenicity 2 protein (ST2) is a member of the interleukin
(IL) 1 receptor family with transmembrane (ST2L) and soluble (sST2) isoforms that are (over) …

A organização de uma diretriz clínica é tarefa complexa, que necessariamente deve
envolver planejamento prévio, coordenação apropriada, revisão aprofundada da literatura …

A organização de uma diretriz clínica é tarefa complexa, que necessariamente deve
envolver planejamento prévio, coordenação apropriada, revisão aprofundada da literatura …

Aims Frailty, characterized by loss of homeostatic reserves and increased vulnerability to
physiological decompensation, results from an aggregation of insults across multiple organ …

Inflammatory bowel disease (IBD) is characterized as chronic inflammation in the
gastrointestinal tract, which includes two main subtypes, Crohn's disease and ulcerative …

Biomarkers such as B-type natriuretic peptide (BNP), N-terminal pro-BNP (NT-proBNP),
cardiac troponin (cTn), and CK-MB contribute significantly to the diagnosis of cardiovascular …

Cardiac fibrosis is associated with non-ischemic dilated cardiomyopathy, increasing its
morbidity and mortality. Cardiac fibroblast is the keystone of fibrogenesis, being activated by …

IL-33 belongs to the IL-1 family of cytokines, which function as inducers of Th2 cytokine
production by binding with ST2L and IL-1RAcP. This, in turn, activates various signaling …

Background Myocarditis is an important cause of acute and chronic heart failure. Men with
myocarditis have worse recovery and an increased need for transplantation compared with …