Abstract Purpose of Review Despite significant progress in recent years, the diagnosis of
periprosthetic joint infection (PJI) remains a challenge and no gold standard test exists. A …

Purpose Periprosthetic joint infection (PJI) is a catastrophic complication after total joint
arthroplasty (TJA). Treatment of PJI is challenging, especially when causative …

Background: Culture-negative periprosthetic joint infection (PJI) is a challenging condition to
treat. The most appropriate management of culture-negative PJI is not known, and there is …

Identification of the causative organism (s) in periprosthetic joint infection (PJI) is a
challenging task. The shortcomings of traditional cultures have been emphasized in recent …

Periprosthetic joint infections (PJI) represent one of the most catastrophic complications
following total joint arthroplasty (TJA). The lack of standardized diagnostic tests and …

The isolation of an infective pathogen can be challenging in some patients with active,
clinically apparent infectious diseases. Despite efforts in the microbiology lab to improve the …

Background: Despite its well-established limitations, culture remains the gold standard for
microbial identification in periprosthetic joint infection (PJI). However, there are no …

Background: Current guidelines recommend serum erythrocyte sedimentation rate (ESR)
and C-reactive protein (CRP) as the first-line testing for evaluation of suspected …

Background The aims of this study were to (1) evaluate the efficacy and safety of targeted
antibiotics for the treatment of culture-negative prosthetic joint infection based on …

Question 1: Do you agree with the American Academy of Orthopaedic Surgeons algorithm
for the diagnosis of periprosthetic joint infections (PJIs)? Recommendation: Yes. However …