Cancer is one of the leading public health issues worldwide, and the number of cancer
patients increases every day. Particularly, cervical cancer (CC) is still the second leading …

Traditionally, protein structures have been analysed by the secondary structure architecture
and fold arrangement. An alternative approach that has shown promise is modelling …

Structural and biochemical studies of the severe acute respiratory syndrome (SARS)-CoV-2
spike glycoproteins and complexes with highly potent antibodies have revealed multiple …

Contact maps are a valuable visualization tool in structural biology. They are a convenient
way to display proteins in two dimensions and to quickly identify structural features such as …

ABSTRACT A key question in immunology is whether antigen recognition and Fc receptor
(FcR) binding are allosterically linked. This question is also relevant for therapeutic antibody …

Correct identification and effective visualization of interactions in biomolecular structures
facilitate understanding of their functions and molecular design. In response to the practical …

Alzheimer's disease is one of the most devastating neurodegenerative diseases without
effective therapies. Immunotherapy is a promising approach, but amyloid antibody structural …

Background Protein inter-residue contact maps provide a translation and rotation invariant
topological representation of a protein. They can be used as an intermediary step in protein …

ChIA-PET is a high-throughput mapping technology that reveals long-range chromatin
interactions and provides insights into the basic principles of spatial genome organization …

Motivation: To date, only a few distinct successful approaches have been introduced to
reconstruct a protein 3D structure from a map of contacts between its amino acid residues (a …