Mesenchymal stem or stromal cells from amnion and umbilical cord tissue and their potential for clinical applications

A Lindenmair, T Hatlapatka, G Kollwig… - Cells, 2012 - mdpi.com
Mesenchymal stem or stromal cells (MSC) have proven to offer great promise for cell-based
therapies and tissue engineering applications, as these cells are capable of extensive self …

Nanoghosts: Harnessing mesenchymal stem cell membrane for construction of drug delivery platforms via optimized biomimetics

Y Xiao, RH Xu, Y Dai - Small, 2024 - Wiley Online Library
Mesenchymal stem cells (MSCs) are becoming hotspots for application in disease therapies
recently, combining with biomaterials and drug delivery system. A major advantage of MSCs …

Coculture of mesenchymal stem cells and endothelial cells enhances host tissue integration and epidermis maturation through AKT activation in gelatin methacryloyl …

X Zhang, J Li, P Ye, G Gao, K Hubbell, X Cui - Acta biomaterialia, 2017 - Elsevier
A major challenge for clinical use of skin substitutes is insufficient host tissue integration
leading to loosening and partial necrosis of the implant. In this present study, a three …

Growth factors-based beneficial effects of platelet lysate on umbilical cord-derived stem cells and their synergistic use in osteoarthritis treatment

L Yan, L Zhou, B Yan, L Zhang, W Du, F Liu… - Cell Death & …, 2020 - nature.com
Poor viability of mesenchymal stem cells (MSCs) at the transplanted site often hinders the
efficacy of MSCs-based therapy. Platelet lysate (PL) contains rich amounts of growth factors …

Diverse impact of xeno-free conditions on biological and regenerative properties of hUC-MSCs and their extracellular vesicles

S Bobis-Wozowicz, K Kmiotek, K Kania… - Journal of Molecular …, 2017 - Springer
Growing evidence indicates that intracellular signaling mediated by extracellular vesicles
(EVs) released by stem cells plays a considerable role in triggering the regenerative …

[HTML][HTML] Stimulating factors for regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells

JQ Zhou, HY Wan, ZX Wang, N Jiang - World Journal of Stem Cells, 2023 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs), distributed in many tissues in the human body, are
multipotent cells capable of differentiating in specific directions. It is usually considered that …

FGF‐2 addition during expansion of human bone marrow‐derived stromal cells alters MSC surface marker distribution and chondrogenic differentiation potential

S Hagmann, B Moradi, S Frank, T Dreher… - Cell …, 2013 - Wiley Online Library
Objectives Although clinical applications using mesenchymal stromal cells (MSC s) are
becoming more frequent, procedures for their in vitro culture are far from standardized …

Immunoregulation of follicular renewal, selection, POF, and menopause in vivo, vs. neo-oogenesis in vitro, POF and ovarian infertility treatment, and a clinical trial

A Bukovsky, MR Caudle - Reproductive Biology and Endocrinology, 2012 - Springer
The immune system plays an important role in the regulation of tissue homeostasis (" tissue
immune physiology"). Function of distinct tissues during adulthood, including the ovary …

Umbilical cord-derived mesenchymal stem cells are able to use bFGF treatment and represent a superb tool for immunosuppressive clinical applications

L Tesarova, K Jaresova, P Simara, I Koutna - International Journal of …, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) have become a promising tool in cellular therapy for
restoring immune system haemostasis; however, the success of clinical trials has been …

The proliferation and stemness of peripheral blood-derived mesenchymal stromal cells were enhanced by hypoxia

P Wang, P Zhu, C Yu, J Wu - Frontiers in endocrinology, 2022 - frontiersin.org
This study aimed to address the dilemma of low peripheral blood-derived mesenchymal
stromal cell (PBMSC) activity and reduced phenotype in bone or cartilage tissue …