We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …

Diabetes in ageing communities imposes a substantial personal and public health burden
by virtue of its high prevalence, its capacity to cause disabling vascular complications, the …

Aims The aim of this study was to derive and validate the SCORE2-Older Persons (SCORE2-
OP) risk model to estimate 5-and 10-year risk of cardiovascular disease (CVD) in individuals …

Every 5 years, the JAS publishes guidelines for the treatment of dyslipidemia and
atherosclerosis. To date, this society has released four such guidelines. Since 2007, the JAS …

Background: Although recent studies suggest that measuring coronary artery calcification
(CAC) may be superior to indirect atherosclerotic markers in predicting cardiac risk, there …

Globally, the number of drug prescriptions is increasing causing more adverse drug events,
which is now a significant cause of mortality, morbidity, and disability that has reached …

Prediction of mortality has focused on disease and frailty, although antecedent biomarkers
may herald broad physiological decline. Olfaction, an ancestral chemical system, is a strong …

Background This guideline focuses on long-term administration of antithrombotic drugs
designed for primary and secondary prevention of cardiovascular disease, including two …

Atherosclerotic cardiovascular diseases (CVDs) are the biggest causes of death worldwide.
In most people, CVD is the product of a number of causal risk factors. Several seemingly …

Advancing age may be the most potent independent predictor of future cardiovascular
events, a relationship that is not fully explained by time‐related changes in traditional …