The cerebrospinal fluid: regulator of neurogenesis, behavior, and beyond

MW Zappaterra, MK Lehtinen - Cellular and molecular life sciences, 2012 - Springer
The cerebrospinal fluid (CSF) has attracted renewed interest as an active signaling milieu
that regulates brain development, homeostasis, and disease. Advances in proteomics …

Inflammatory regulation of CNS barriers after traumatic brain injury: a tale directed by interleukin-1

CN Bodnar, JB Watson, EK Higgins, N Quan… - Frontiers in …, 2021 - frontiersin.org
Several barriers separate the central nervous system (CNS) from the rest of the body. These
barriers are essential for regulating the movement of fluid, ions, molecules, and immune …

Deep dive on the proteome of human cerebrospinal fluid: a valuable data resource for biomarker discovery and missing protein identification

C Macron, L Lane, A Núñez Galindo… - Journal of proteome …, 2018 - ACS Publications
Cerebrospinal fluid (CSF) is a body fluid of choice for biomarker studies of brain disorders
but remains relatively under-studied compared with other biological fluids such as plasma …

Social stress increases expression of hemoglobin genes in mouse prefrontal cortex

AM Stankiewicz, J Goscik, AH Swiergiel, A Majewska… - BMC neuroscience, 2014 - Springer
Background In order to better understand the effects of social stress on the prefrontal cortex,
we investigated gene expression in mice subjected to acute and repeated social encounters …

The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury

J Xiang, LJ Routhe, DA Wilkinson, Y Hua… - Fluids and Barriers of …, 2017 - Springer
While the impact of hemorrhagic and ischemic strokes on the blood–brain barrier has been
extensively studied, the impact of these types of stroke on the choroid plexus, site of the …

Meningeal and choroid plexus cells—Novel drug targets for CNS disorders

M Dragunow - Brain research, 2013 - Elsevier
The meninges and choroid plexus perform many functions in the developing and adult
human central nervous system (CNS) and are composed of a number of different cell types …

Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease

J Chung, X Zhang, M Allen, X Wang, Y Ma… - Alzheimer's research & …, 2018 - Springer
Background Simultaneous consideration of two neuropathological traits related to
Alzheimer's disease (AD) has not been attempted in a genome-wide association study …

Altered endocannabinoid metabolism compromises the brain-CSF barrier and exacerbates chronic deficits after traumatic brain injury in mice

M Ahluwalia, H Mcmichael, M Kumar… - Experimental …, 2023 - Elsevier
Abstract Endocannabinoids [2-arachidonoylglycerol (2-AG) and N-
arachidonoylethanolamine (AEA)], endogenously produced arachidonate-based lipids, are …

Synthesis of β-thiol phenylalanine for applications in one-pot ligation–desulfurization chemistry

LR Malins, AM Giltrap, LJ Dowman, RJ Payne - Organic letters, 2015 - ACS Publications
The efficient synthesis of a β-thiol phenylalanine derivative is described starting from
Garner's aldehyde. The utility of this amino acid in peptide ligation–desulfurization chemistry …

Proliferation of cultured mouse choroid plexus epithelial cells

BZ Barkho, ES Monuki - PLoS One, 2015 - journals.plos.org
The choroid plexus (ChP) epithelium is a multifunctional tissue found in the ventricles of the
brain. The major function of the ChP epithelium is to produce cerebrospinal fluid (CSF) that …