Thyroid dysfunction and diabetes mellitus are closely linked. Several studies have
documented the increased prevalence of thyroid disorders in patients with diabetes mellitus …

Generation, transformation, and utilization of organic molecules in support of cellular
differentiation, growth, and maintenance are basic tenets that define life. In eukaryotes …

Thyroid hormone (TH) is required for normal development as well as regulating metabolism
in the adult. The thyroid hormone receptor (TR) isoforms, α and β, are differentially …

Hypothalamic pro-opiomelanocortin (POMC) neurons promote satiety. Cannabinoid
receptor 1 (CB 1 R) is critical for the central regulation of food intake. Here we test whether …

The fertility and survival of an individual rely on the ability of the periphery to promptly,
effectively, and reproducibly communicate with brain neural networks that control …

Thyroid hormones have widespread cellular effects; however it is unclear whether their
effects on the central nervous system (CNS) contribute to global energy balance. Here we …

The iodothyronine deiodinases initiate or terminate thyroid hormone action and therefore
are critical for the biological effects mediated by thyroid hormone. Over the years, research …

TRH is a tripeptide amide that functions as a neurotransmitter but also serves as a
neurohormone that has a critical role in the central regulation of the hypothalamic-pituitary …

Obesity and thyroid diseases are common disorders in the general population and they
frequently occur in single individuals. Alongside a chance association, a direct relationship …

The gut-derived hormone ghrelin exerts its effect on the brain by regulating neuronal activity.
Ghrelin-induced feeding behaviour is controlled by arcuate nucleus neurons that co-express …