Radioprotective agents to prevent cellular damage due to ionizing radiation

TA Smith, DR Kirkpatrick, S Smith, TK Smith… - Journal of translational …, 2017 - Springer
Medical imaging has become a central component of patient care to ensure early and
accurate diagnosis. Unfortunately, many imaging modalities use ionizing radiation to …

[HTML][HTML] HIF-1α protects against oxidative stress by directly targeting mitochondria

HS Li, YN Zhou, L Li, SF Li, D Long, XL Chen… - Redox biology, 2019 - Elsevier
The transcription factor hypoxia inducible factor-1α (HIF-1α) mediates adaptive responses to
oxidative stress by nuclear translocation and regulation of gene expression. Mitochondrial …

Induction of ferroptosis by HO-1 contributes to retinal degeneration in mice with defective clearance of all-trans-retinal

C Chen, K Yang, D He, B Yang, L Tao, J Chen… - Free Radical Biology and …, 2023 - Elsevier
The accumulation of all-trans-retinal (atRAL) in photoreceptors and the retinal pigment
epithelium (RPE), which is induced by chaos in visual (retinoid) cycle, is closely associated …

The role of DNA repair genes in radiation-induced adaptive response in Drosophila melanogaster is differential and conditional

L Koval, E Proshkina, M Shaposhnikov, A Moskalev - Biogerontology, 2020 - Springer
Studies in human and mammalian cell cultures have shown that induction of DNA repair
mechanisms is required for the formation of stimulation effects of low doses of ionizing …

Carbon Monoxide Releasing Molecule‐3 Enhances Heme Oxygenase‐1 Induction via ROS‐Dependent FoxO1 and Nrf2 in Brain Astrocytes

CC Lin, CC Yang, LD Hsiao… - Oxidative Medicine and …, 2021 - Wiley Online Library
Carbon monoxide releasing molecule‐3 (CORM‐3) has been shown to protect inflammatory
diseases via the upregulation of heme oxygenases‐1 (HO‐1). However, in rat brain …

Gender differences in cancer susceptibility: role of oxidative stress

I Ali, J Högberg, JH Hsieh, S Auerbach… - …, 2016 - academic.oup.com
Cancer is a leading cause of death worldwide and environmental factors, including
chemicals, have been suggested as major etiological incitements. Cancer statistics indicates …

Flying by the seat of our pants: is low dose radiation therapy for COVID-19 an option?

D Schaue, WH McBride - International journal of radiation biology, 2020 - Taylor & Francis
The discovery of X-rays in 1895 had a dramatic impact on many aspects of society. One was
the hope that it would be possible to treat some of the numerous infections and inflammatory …

Low-dose gamma radiation modulates liver and testis tissues response to acute whole body irradiation

N Abdel-Aziz, RAH Haroun, HE Mohamed - Dose-Response, 2022 - journals.sagepub.com
Aim This work aims to investigate whether the pre-exposure to low dose/low dose rate (40
mGy, 2.2 mGy/hour) γ-radiation as a priming dose can produce a protective effect against …

[HTML][HTML] Bilirubin represents a negative regulator of ILC2 in allergic airway inflammation

J He, G Jiang, X Li, Q Xiao, Y Chen, H Xu, G Liu… - Mucosal …, 2022 - Elsevier
Group 2 innate lymphoid cells (ILC2s) play an important role in allergic airway inflammation.
Despite recent advances in defining molecular mechanisms that control ILC2 development …

The combination of new immunotherapy and radiotherapy: an ew potential treatment for locally advanced non-small cell lung cancer

PC Sacco, P Maione, C Guida… - Current Clinical …, 2017 - ingentaconnect.com
Lung cancer is the main reason of cancer death worldwide. About 30% of non-small-cell
lung cancer (NSCLC) cases are diagnosed with locally advanced disease (stage III). This is …