Lung cancer is one of the malignant tumors that seriously threaten human health worldwide,
while the covid-19 virus has become people's nightmare after the coronavirus pandemic …

Triple-negative breast cancer (TNBC) is one of the most aggressive types of cancer, and
treatment is limited to chemotherapy and radiation. Oncolytic virotherapy may be a …

While clinical responses to palbociclib have been promising, metastatic breast cancer
remains incurable due to the development of resistance. We generated estrogen receptor …

Lung cancer is the most prevalent cause of cancer deaths in men and women, with a 5-year
survival rate of fewer than 15% due to late-stage diagnosis and ineffective treatments …

Adenoviruses (Ads) have been extensively manipulated for the development of cancer
selective replication, leading to cancer cell death or oncolysis. Clinical studies using E1 …

The preclinical evaluation of oncolytic adenoviruses (OAds) has been limited to cancer
xenograft mouse models because OAds replicate poorly in murine cancer cells. The …

Oncolytic adenoviruses (Ads) are cancer selective tumoricidal agents; however their
mechanism of Ad-mediated cancer cell lysis, or oncolysis, remains undefined. This report …

Viral laboratory evolution has been used for different applications, such as modeling viral
emergence, drug-resistance prediction, and therapeutic virus optimization. However, these …

Oncolytic adenoviruses (Ads) have great therapeutic potential for lung cancer treatment.
Cancer selective E1b-deleted Ads are safe; however, their clinical cancer therapeutic …