Increased mortality in rheumatoid arthritis (RA) is widely recognized but not fully explained.
Despite substantial improvements in management and growing knowledge of the …

Abstract “Rhupus” or “rhupus syndrome” is a poorly described and underdiagnosed disease
in which features of both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) …

Systemic lupus erythematosus is a heritable autoimmune disease that predominantly affects
young women. To improve our understanding of genetic etiology, we conduct multi-ancestry …

Metabolic fingerprints in serum characterize diverse diseases for diagnostics and biomarker
discovery. The identification of systemic lupus erythematosus (SLE) by serum metabolic …

Objective Infection risk is increased in patients with rheumatoid arthritis (RA), and accurate
assessment of the risk of infection could inform clinical decision‐making. This study was …

The central pathogenetic role of type I interferons (IFNs) in several systemic autoimmune
diseases is well established. Recent studies have also discovered a similar crucial role of …

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by
the production of antinuclear autoantibodies and the inflammatory infiltration of many organ …

The concept that autoimmune diseases are characterized by shared (common) threads is
well illustrated by their propensity to co-associate in a patient or direct relatives, as …

Background The concomitant presence of two autoimmune diseases–systemic lupus
erythematosus (SLE) and rheumatoid arthritis (RA)–in the same patient is known as rhupus …

Background Clinical and epidemiological studies have suggested systemic lupus
erythematosus (SLE) and rheumatoid arthritis (RA) are comorbidities and common genetic …