Myotonic dystrophy type 1 (DM1) is the most common muscular dystrophy that affects
multiple systems including the muscle and heart. The mutant CTG expansion at the 3′-UTR …

Increasing evidences indicate that in Myotonic Dystrophy type 1 (DM1 or Steinert disease),
an autosomal dominant multisystem disorder caused by a (CTG) n expansion in DMPK gene …

Abstract Myotonic Dystrophy Type 1 (DM1) is a multisystemic disease that affects gray and
white matter (WM) tissues. WM changes in DM1 include increased hyperintensities and …

Purpose Myotonic dystrophy type 1 (DM1) is a muscular dystrophy with neurological,
cognitive, and radiological abnormalities. The developmental or degenerative nature of …

Myotonic dystrophy type 1 is the most common form of muscular dystrophy in adults, and is
primarily characterized by muscle weakness and myotonia, yet some of the most disabling …

Objective To characterize the progression of brain structural abnormalities in adults with
pediatric and adult/late onset DM1, as well as to examine the potential predictive markers of …

Aim To delineate the neurogenetic profiles of brain degeneration patterns in myotonic
dystrophy type I (DM1). Methods In two cohorts of DM1 patients, brain maps of volume loss …

Myotonic dystrophy type 1 (DM1) is a genetic disorder caused by a (CTG) expansion in the
DM protein kinase (DMPK) gene, representing the most common adult muscular dystrophy …

Myotonic dystrophy (DM) encompasses a spectrum of neuromuscular diseases
characterized by myotonia, muscle weakness, and wasting. Recent research has led to the …

Abstract Objective To investigate Tau pathology using multimodal biomarkers of
neurodegeneration and neurocognition in participants with myotonic dystrophy type 1 …