The proximity and continuity of the oral cavity and the lower respiratory tract allows the
oropharyngeal microbiome to be a major determinant of the lung microbiome. In addition …

Cystic fibrosis is a multiorgan disease caused by impaired function of the cystic fibrosis
transmembrane conductance regulator (CFTR). Since the introduction of the CFTR …

Recent studies of human respiratory secretions using culture-independent techniques have
found a surprisingly diverse array of microbes. Interactions among these community …

Background Pseudomonas aeruginosa (PA) is an important respiratory pathogen for cystic
fibrosis (CF) patients. Routine microbiology surveillance is time-consuming, and is best …

Cyanobacteria produce harmful toxins that have been associated with several acute
conditions and chronic human diseases, like gastroenteritis, non-alcoholic liver disease, and …

Background An electronic nose (eNose) can be used to detect volatile organic compounds
(VOCs). Exhaled breath contains numerous VOCs and individuals' VOCs mixtures create …

Respiratory infections caused by Pseudomonas aeruginosa and Staphylococcus aureus are
the leading cause of morbidity and mortality in cystic fibrosis (CF) patients. The authors …

Staphylococcus aureus (S. aureus) is a common bacterium infecting children with cystic
fibrosis (CF). Since current detection methods are difficult to perform in children, there is …

The human pathogens Pseudomonas aeruginosa and Staphylococcus aureus are
frequently co-isolated from chronic wounds or cystic fibrosis patient airways. Clinical studies …

Background Numerous pulmonary diseases manifest with upper lobe predominance
including cystic fibrosis, smoking-related chronic obstructive pulmonary disease, and …