Objective To assess the associations between statins and adverse events in primary
prevention of cardiovascular disease and to examine how the associations vary by type and …

Objectives To summarise existing evidence on a target oriented approach for rheumatoid
arthritis (RA) treatment. Methods We conducted a systematic literature search including all …

Aim of the present Consensus Statement is to provide a comprehensive and up to-date
document on the pathophysiology, atherogenicity and clinical significance of low density …

Background The effects of statin administration on kidney disease outcomes remain
controversial. We undertook a systematic review and meta-analysis to assess the efficacy of …

Purpose The objective was to systematically review clinical trial data on the effects of statins
on high-density lipoproteins (HDL) and to examine the possibility that this provides …

The focus of this review is on the role of apolipoprotein C-II (apoC-II) in lipoprotein
metabolism and the potential effects on the risk of cardiovascular disease (CVD). We …

Elevated serum uric acid (SUA) levels (ie hyperuricaemia) have been associated with
metabolic syndrome (MetS) and cardiovascular disease (CVD) morbidity and mortality …

HMG-CoA reductase inhibitors (statins) are the mainstay in the pharmacologic management
of dyslipidemia. Since they are widely prescribed, their safety remains an issue of concern …

Drug-induced hyperuricemia and gout present an increasingly prevalent problem in clinical
practice. Herein, we review the urate-lowering or urate-raising effects of commonly used …

Aim: Five multicentre, cross-sectional Centralized Pan-Regional Surveys on the
Undertreatment of Hypercholesterolaemia (CEPHEUS) were conducted in 29 countries …