Relevance of interactions between dopamine and glutamate neurotransmission in schizophrenia
Dopamine (DA) and glutamate neurotransmission are strongly implicated in schizophrenia
pathophysiology. While most studies focus on contributions of neurons that release only DA …
pathophysiology. While most studies focus on contributions of neurons that release only DA …
The heterogeneity of Parkinson's disease
U Wüllner, P Borghammer, C Choe, I Csoti… - Journal of Neural …, 2023 - Springer
The heterogeneity of Parkinson's disease (PD), ie the various clinical phenotypes,
pathological findings, genetic predispositions and probably also the various implicated …
pathological findings, genetic predispositions and probably also the various implicated …
Hormones and sex-specific medicine in human physiopathology
MR Tokatli, LG Sisti, E Marziali, L Nachira, MF Rossi… - Biomolecules, 2022 - mdpi.com
A prodigious increment of scientific evidence in both preclinical and clinical studies is
narrowing a major gap in knowledge regarding sex-specific biological responses observed …
narrowing a major gap in knowledge regarding sex-specific biological responses observed …
Sex differences in dopaminergic vulnerability to environmental toxicants—implications for Parkinson's disease
Abstract Purpose of Review Sex dimorphism in Parkinson's disease (PD) is an ostensible
feature of the neurological disorder, particularly as men are 1.5–2 times more likely to …
feature of the neurological disorder, particularly as men are 1.5–2 times more likely to …
Roles of VGLUT2 and dopamine/glutamate co-transmission in selective vulnerability to dopamine neurodegeneration
SA Buck, MQ Erickson-Oberg, SH Bhatte… - ACS chemical …, 2022 - ACS Publications
Growing evidence has established that a subset of dopamine (DA) neurons co-release
glutamate and express vesicular glutamate transporter 2 (VGLUT2). VGLUT2 expression in …
glutamate and express vesicular glutamate transporter 2 (VGLUT2). VGLUT2 expression in …
Alterations in neurotransmitter co-release in Parkinson's disease
K Barcomb, CP Ford - Experimental Neurology, 2023 - Elsevier
Parkinson's disease is a neurological disorder characterized by degeneration of midbrain
dopamine neurons, which results in numerous adaptations in basal ganglia circuits …
dopamine neurons, which results in numerous adaptations in basal ganglia circuits …
Ventral pallidal GABAergic neuron calcium activity encodes cue-driven reward seeking and persists in the absence of reward delivery
A Scott, D Palmer, B Newell, I Lin… - Journal of …, 2023 - Soc Neuroscience
Reward-seeking behavior is often initiated by environmental cues that signal reward
availability. This is a necessary behavioral response; however, cue reactivity and reward …
availability. This is a necessary behavioral response; however, cue reactivity and reward …
A mini-review of the role of vesicular glutamate transporters in Parkinson's disease
C Zhao, C Wang, H Zhang, W Yan - Frontiers in Molecular …, 2023 - frontiersin.org
Parkinson's disease (PD) is a common neurodegenerative disease implicated in multiple
interacting neurotransmitter pathways. Glutamate is the central excitatory neurotransmitter in …
interacting neurotransmitter pathways. Glutamate is the central excitatory neurotransmitter in …
Transient MPTP exposure at a sensitive developmental window altered gut microbiome and led to male-biased motor and social behavioral deficits in adult zebrafish
H Dong, H Wu, C Bai, K Ye, L Mao, Y Lei, Y Liu, H Xu… - NeuroToxicology, 2022 - Elsevier
Zebrafish is an economical alternative model for developmental neurotoxicity (DNT) testing.
DNT studies in zebrafish have been focused on acute effects; few studies explore enduring …
DNT studies in zebrafish have been focused on acute effects; few studies explore enduring …
Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease
T Steinkellner, WS Conrad, I Kovacs, RA Rissman… - Brain, 2022 - academic.oup.com
Loss of midbrain dopamine neurons causes the cardinal symptoms of Parkinson's disease.
However, not all dopamine neurons are equally vulnerable and a better understanding of …
However, not all dopamine neurons are equally vulnerable and a better understanding of …