Pharmacotherapy for neuropsychiatric disorders, such as anxiety and depression, has been
characterized by significant inter-individual variability in drug response and the development …

The P‐glycoprotein efflux pump, encoded by the ABCB1 gene, has been shown to alter
concentrations of various antidepressants in the brain. In this study, we conducted a …

Drug therapy is the primary modality for depression; however, its outcome is often
unpredictable, ranging from beneficial effects to serious adverse effects. Genetic variations …

Introduction The importance of identifying relevant indicators of antidepressant efficacy is
highlighted by the low response rates to antidepressant treatment for depression. The ABC …

Genetic factors influence medication response (pharmacogenetics), affecting the
pharmacodynamics and pharmacokinetics of many medicaments used in clinical care. The …

This article develops the idea that clinical depression can be seen as a typical human
response, largely rooted in human culture, to events of loss or times of adversity. Various …

Many individuals with schizophrenia also suffer from metabolic syndrome (MetS), which is a
major risk factor for the development of cardiovascular disroders associated with a heavy …

Many individuals with schizophrenia also suffer from metabolic syndrome (MetS), which is a
major risk factor for the development of cardiovascular diseases associated with a heavy …