Microglia are the resident macrophages of the central nervous system. Microglia possess
varied morphologies and functions. Under normal physiological conditions, microglia mainly …

Major depression is a leading contributor to the global burden of disease. This situation is
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …

Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

Depression is widely acknowledged to be a heterogeneous entity, and the need to further
characterize the individual patient who has received this diagnosis in order to personalize …

The mammalian brain is a complex organ comprising neurons, glia, and more than 1× 1014
synapses. Neurons are a heterogeneous group of electrically active cells, which form the …

Attention is the gate through which sensory information enters our conscious experiences.
Oftentimes, patients with major depressive disorder (MDD) complain of concentration …

Introduction Major depressive disorder (MDD) is a global psychiatric disorder with no
established biomarker. There is growing evidence that functional near-infrared spectroscopy …

Importance Cognitive deficits in depression have been associated with poor functional
capacity, frontal neural circuit dysfunction, and worse response to conventional …

Depression is a worldwide health issue to which various physical, psychological, and social
health problems are attributable. To address the issue through the promotion of digital …

Background Major depressive disorder is a widespread mood disorder. One of the most
debilitating symptoms patients often experience is cognitive impairment. Recent findings …