The gut microbiome and HIV-1 pathogenesis: a two-way street

SM Dillon, DN Frank, CC Wilson - Aids, 2016 - journals.lww.com
HIV-1 infection is associated with substantial damage to the gastrointestinal tract resulting in
structural impairment of the epithelial barrier and a disruption of intestinal homeostasis. The …

Altered gut microbiome composition in HIV infection: causes, effects and potential intervention

A Bandera, I De Benedetto, G Bozzi… - Current opinion in HIV …, 2018 - journals.lww.com
Studying the human host–microbiota interaction suggests that the consequences of HIV
infection on microbial composition can influence immune status in HIV patients. ART …

Probiotic cell‐free supernatants exhibited anti‐inflammatory and antioxidant activity on human gut epithelial cells and macrophages stimulated with LPS

S De Marco, M Sichetti, D Muradyan… - Evidence‐Based …, 2018 - Wiley Online Library
The incidence of inflammatory bowel disease is increasing all over the world, especially in
industrialized countries. The aim of the present work was to verify the anti‐inflammatory …

[HTML][HTML] Probiotic supplementation in diabetic hemodialysis patients has beneficial metabolic effects

A Soleimani, MZ Mojarrad, F Bahmani, M Taghizadeh… - Kidney international, 2017 - Elsevier
This study determined the effects of probiotic supplementation on glycemic control, lipid
concentrations, biomarkers of inflammation and oxidative stress in 60 diabetic patients on …

Probiotic supplementation promotes a reduction in T‐cell activation, an increase in Th17 frequencies, and a recovery of intestinal epithelium integrity and …

G d'Ettorre, G Rossi, C Scagnolari… - Immunity …, 2017 - Wiley Online Library
Introduction HIV infection is characterized by a persistent immune activation associated to a
compromised gut barrier immunity and alterations in the profile of the fecal flora linked with …

Gut microbiome alterations during HIV/SIV infection: implications for HIV cure

KR Crakes, G Jiang - Frontiers in microbiology, 2019 - frontiersin.org
Gut mucosal damage, associated with Human Immunodeficiency Virus-1 (HIV) infection, is
characterized by depletion in CD4+ T cells and persistent immune activation as a result of …

Microbiota and probiotics in health and HIV infection

C D'Angelo, M Reale, E Costantini - Nutrients, 2017 - mdpi.com
Microbiota play a key role in various body functions, as well as in physiological, metabolic,
and immunological processes, through different mechanisms such as the regulation of the …

Microbiome alterations in HIV infection a review

B Williams, A Landay, RM Presti - Cellular microbiology, 2016 - Wiley Online Library
Recent developments in molecular techniques have allowed researchers to identify
previously uncultured organisms, which has propelled a vast expansion of our knowledge …

Complexities of gut microbiome dysbiosis in the context of HIV infection and antiretroviral therapy

SX Li, AJS Armstrong, CP Neff… - Clinical …, 2016 - Wiley Online Library
Human immunodeficiency virus (HIV) infection is associated with an altered gut microbiome
that is not consistently restored with effective antiretroviral therapy (ART). Interpretation of …

Regulation of gut microbiota on immune reconstitution in patients with acquired immunodeficiency syndrome

ST Geng, ZY Zhang, YX Wang, D Lu, J Yu… - Frontiers in …, 2020 - frontiersin.org
Human immunodeficiency virus type 1 (HIV-1) infection of CD4+ T cells in the gut plays an
insidious role in acquired immunodeficiency syndrome (AIDS) pathogenesis. Host immune …