Uterine tumors resembling ovarian sex-cord tumors (UTROSCT) are thought to develop from
pluripotent uterine mesenchymal cells or endometrial stromal cells with secondary sex-cord …

The systemic therapy management of metastatic colorectal cancer (mCRC) has evolved
from primarily cytotoxic chemotherapies to now include targeted agents given alone or in …

Simple Summary Due to the increase of molecular biomarkers to be characterized to tailor
therapeutic strategies for non-squamous non-small cell lung carcinoma (NS-NSCLC), it is …

Cytopathology represents a well established diagnostic approach because of its limited cost,
reliability, and minimal invasiveness with respect to other methodologies. The evolving …

Genetic factors have long been recognized as important determinants of interindividual
variability in drug efficacy and toxicity. However, despite the increasing number of …

The relevant study of transcriptome-wide variations and neurological disorders in the
evolved field of genomic data science is on the rise. Deep learning has been highlighted …

Next-generation sequencing offers highly multiplexed and accurate detection of nucleic acid
sequences but at the expense of complex workflows and high input requirements. The ease …

PURPOSE Targeted therapy yields superior outcomes relative to genotype-agnostic therapy
for patients with epidermal growth factor receptor (EGFR)-mutant lung cancer. Workflows …

Abstract Fluoropyrimidines (FLs)[5-Fluorouracil, Capecitabine] are used in the treatment of
several solid tumors. Dihydropyrimidine dehydrogenase (DPD) is the rate-limiting enzyme …

ABSTRACT Background Circulating tumor DNA (ctDNA) positivity at diagnosis, which is
associated with worse outcomes in multiple solid tumors including stage I–III non-small cell …