Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …

Metazoan tissue specification is associated with integration of macrophage lineage cells in
sub-tissular niches to promote tissue development and homeostasis. Oncogenic …

New and provocative insights into the relationships between iron and cancer have been
uncovered in recent years. These include delineation of connections that link cellular iron to …

High-grade gliomas, the most common and aggressive primary brain tumors, are
characterized by a complex tumor microenvironment (TME). Among the immune cells …

Inflammation is now recognized as a hallmark of cancer. Genetic changes in the cancer cell
are accepted as the match that lights the fire, whilst inflammation is seen as the fuel that …

There is new and increasing evidence from in vitro, in vivo and clinical studies implicating
the pivotal role of iron and associated metabolic pathways in the initiation, progression and …

Macrophage immunotherapy represents an emerging therapeutic approach aimed at
modulating the immune response to alleviate disease symptoms. Nanomaterials (NMs) have …

The tumor bulk is composed of a highly heterogeneous population of cancer cells, as well as
a large variety of resident and infiltrating host cells, extracellular matrix proteins, and …

Macrophages fulfill central functions in systemic iron metabolism and immune response.
Infiltration and polarization of macrophages in the tumor microenvironment is associated …

Metal ions, such as selenium, copper, zinc, and iron are naturally present in the environment
(air, drinking water, and food) and are vital for cellular functions at chemical, molecular, and …