Neurotransmitters—key factors in neurological and neurodegenerative disorders of the central nervous system
Neurotransmitters are molecules that amplify, transmit, and convert signals in cells, having
an essential role in information transmission throughout the nervous system. Hundreds of …
an essential role in information transmission throughout the nervous system. Hundreds of …
Cannabinoids: therapeutic use in clinical practice
Medical case reports suggest that cannabinoids extracted from Cannabis sativa have
therapeutic effects; however, the therapeutic employment is limited due to the psychotropic …
therapeutic effects; however, the therapeutic employment is limited due to the psychotropic …
Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy
SARS-CoV-2 messenger RNA vaccination in healthy individuals generates immune
protection against COVID-19. However, little is known about SARS-CoV-2 mRNA vaccine …
protection against COVID-19. However, little is known about SARS-CoV-2 mRNA vaccine …
Potential drug targets for multiple sclerosis identified through Mendelian randomization analysis
J Lin, J Zhou, Y Xu - Brain, 2023 - academic.oup.com
Multiple sclerosis is a complex autoimmune disease, and several therapies for multiple
sclerosis have been developed and widely used. However, existing medications for multiple …
sclerosis have been developed and widely used. However, existing medications for multiple …
Humoral-and T-cell–specific immune responses to SARS-CoV-2 mRNA vaccination in patients with MS using different disease-modifying therapies
Background and Objectives To evaluate the immune-specific response after full severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination of patients with …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination of patients with …
Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression
E Van San, AC Debruyne, G Veeckmans… - Cell Death & …, 2023 - nature.com
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by central nervous
(CNS) demyelination resulting in axonal injury and neurological deficits. Essentially, MS is …
(CNS) demyelination resulting in axonal injury and neurological deficits. Essentially, MS is …
Inflammasome assembly in neurodegenerative diseases
J Singh, ML Habean, N Panicker - Trends in Neurosciences, 2023 - cell.com
Neurodegenerative disorders are characterized by the progressive dysfunction and death of
selectively vulnerable neuronal populations, often associated with the accumulation of …
selectively vulnerable neuronal populations, often associated with the accumulation of …
Thinking outside the box: non-canonical targets in multiple sclerosis
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system that
causes demyelination, axonal degeneration and astrogliosis, resulting in progressive …
causes demyelination, axonal degeneration and astrogliosis, resulting in progressive …
[HTML][HTML] Multiple sclerosis therapies differentially affect SARS-CoV-2 vaccine–induced antibody and T cell immunity and function
JJ Sabatino Jr, K Mittl, WM Rowles, K McPolin… - JCI insight, 2022 - ncbi.nlm.nih.gov
BACKGROUND Vaccine-elicited adaptive immunity is a prerequisite for control of SARS-
CoV-2 infection. Multiple sclerosis (MS) disease-modifying therapies (DMTs) differentially …
CoV-2 infection. Multiple sclerosis (MS) disease-modifying therapies (DMTs) differentially …
Multiple sclerosis and myelin basic protein: Insights into protein disorder and disease
V Martinsen, P Kursula - Amino Acids, 2022 - Springer
Myelin basic protein (MBP) is an abundant protein in central nervous system (CNS) myelin.
MBP has long been studied as a factor in the pathogenesis of the autoimmune …
MBP has long been studied as a factor in the pathogenesis of the autoimmune …