Anxiolytic and antidepressive potentials of rosmarinic acid: A review with a focus on antioxidant and anti-inflammatory effects

A Dahchour - Pharmacological Research, 2022 - Elsevier
Depression and anxiety are the most prevalent neuropsychiatric disorders that have
emerged as global health concerns. Anxiolytic and antidepressant drugs, such as …

Polyphenols: A route from bioavailability to bioactivity addressing potential health benefits to tackle human chronic diseases

S Vivarelli, C Costa, M Teodoro, F Giambò… - Archives of …, 2023 - Springer
Chronic pathologies or non-communicable diseases (NCDs) include cardiovascular
diseases, metabolic syndrome, neurological diseases, respiratory disorders and cancer …

In vitro study of the PLA2 inhibition and antioxidant activities of Aloe vera leaf skin extracts

M Kammoun, S Miladi, YB Ali, M Damak… - Lipids in health and …, 2011 - Springer
Background In the present work we determined the total phenolic content of Aloe vera leaf
skin (AVLS) extracts by using various solvents (hexane, chloroform-ethanol (1/1), ethyl …

From fangs to pharmacology: the future of snakebite envenoming therapy

AH Laustsen, M Engmark, C Milbo… - Current …, 2016 - ingentaconnect.com
The snake is the symbol of medicine due to its association with Asclepius, the Greek God of
medicine, and so with good reasons. More than 725 species of venomous snakes have …

Snake Venom PLA2s Inhibitors Isolated from Brazilian Plants: Synthetic and Natural Molecules

BMA Carvalho, JDL Santos, BM Xavier… - BioMed Research …, 2013 - Wiley Online Library
Ophidian envenomation is an important health problem in Brazil and other South American
countries. In folk medicine, especially in developing countries, several vegetal species are …

Isolation and characterization of ellagic acid derivatives isolated from Casearia sylvestris SW aqueous extract with anti-PLA2 activity

SL Da Silva, AK Calgarotto, JS Chaar, S Marangoni - Toxicon, 2008 - Elsevier
The Casearia sylvestris SW (Flacourtiaceae) is utilized in folk medicine (Brazil and all Latin
American) to treat several pathologic processes as inflammation, cancer, microbial infection …

Impact of the inhibition of proteins activities and the chemical aspect of polyphenols-proteins interactions

NS Adrar, K Madani, S Adrar - PharmaNutrition, 2019 - Elsevier
The good nutritional value and the interesting biological activities of the plant-based
nutraceuticals are primarily due to the polyphenols. These latter are among the most …

Targeting tissue oxidative damage by means of cell signaling modulators: the antioxidant concept revisited

G Leonarduzzi, B Sottero, G Poli - Pharmacology & therapeutics, 2010 - Elsevier
The complex system of molecular communications underlying cell biochemistry and function
includes numerous components, kinases, phosphatases and transcription factors, that have …

Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes

BMM de Oliveira, PZ Serpa… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological importance Casearia sylvestris Sw.(Salicaceae) is a native
plant from the Americas, where it is also known as “guaçatonga” or “erva-de-bugre.” …

Bioactive phytonutrients (omega fatty acids, tocopherols, polyphenols), in vitro inhibition of nitric oxide production and free radical scavenging activity of non-cultivated …

F Conforti, M Marrelli, C Carmela, F Menichini… - Food chemistry, 2011 - Elsevier
Hydroalcoholic extracts from 18 non-cultivated vegetables traditionally consumed in
Southern Italy were tested for their free radical scavenging activity (FRSA) in the DPPH (1, 1 …