Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability

H Wang, T Oo Khor, L Shu, ZY Su… - Anti-Cancer Agents …, 2012 - ingentaconnect.com
Cancer remains to be one of the leading causes of death in the United States and around
the world. The advent of modern drug-targeted therapies has undeniably improved cancer …

Plant-derived bioactives and oxidative stress-related disorders: a key trend towards healthy aging and longevity promotion

B Salehi, E Azzini, P Zucca, E Maria Varoni… - Applied Sciences, 2020 - mdpi.com
Plants and their corresponding botanical preparations have been used for centuries due to
their remarkable potential in both the treatment and prevention of oxidative stress-related …

Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges

E Shankar, R Kanwal, M Candamo, S Gupta - Seminars in cancer biology, 2016 - Elsevier
The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …

Targeted regulation of PI3K/Akt/mTOR/NF-κB signaling by indole compounds and their derivatives: mechanistic details and biological implications for cancer therapy

A Ahmad, B Biersack, Y Li, D Kong… - Anti-Cancer Agents …, 2013 - ingentaconnect.com
Indole compounds, found in cruciferous vegetables, are potent anti-cancer agents. Studies
with indole-3-carbinol (I3C) and its dimeric product, 3, 3'-diindolylmethane (DIM) suggest …

Cymbopogon citratus and Cymbopogon giganteus essential oils have cytotoxic effects on tumor cell cultures. Identification of citral as a new putative anti-proliferative …

B Bayala, IHN Bassole, S Maqdasy, S Baron… - Biochimie, 2018 - Elsevier
Cymbopogon species are used as traditional remedies in Burkina Faso for treating several
diseases. We aimed to study the effects of their essential oils on cancer cell lines. For that …

Regulation of microRNAs by natural agents: new strategies in cancer therapies

NH Phuah, NH Nagoor - BioMed research international, 2014 - Wiley Online Library
MicroRNAs (miRNAs) are short noncoding RNA which regulate gene expression by
messenger RNA (mRNA) degradation or translation repression. The plethora of published …

Plant-derived epigenetic modulators for cancer treatment and prevention

M Schnekenburger, M Dicato, M Diederich - Biotechnology advances, 2014 - Elsevier
Carcinogenesis is a complex and multistep process that involves the accumulation of
successive transformational events driven by genetic mutations and epigenetic alterations …

[HTML][HTML] MicroRNA targeted therapeutic approach for pancreatic cancer

Y Li, FH Sarkar - International journal of biological sciences, 2016 - ncbi.nlm.nih.gov
Pancreatic cancer remains the fourth leading cause of cancer-related death in the US and is
expected to be the second leading cause of cancer-related death by 2030. Therefore, it is …

Anti-inflammatory and anti-oxidant effects of Cardamom (Elettaria repens (Sonn.) Baill) and its phytochemical analysis by 4D GCXGC TOF-MS

HK Kandikattu, P Rachitha, GV Jayashree… - Biomedicine & …, 2017 - Elsevier
Elleteria repens is a large cardamom used in the culinary preparations. In the present study,
we have evaluated in vitro antioxidant and free radical scavenging activities E. repens …

[HTML][HTML] Simultaneous inhibition of cell-cycle, proliferation, survival, metastatic pathways and induction of apoptosis in breast cancer cells by a phytochemical super …

A Ouhtit, RL Gaur, M Abdraboh, SK Ireland… - Journal of …, 2013 - ncbi.nlm.nih.gov
Traditional chemotherapy and radiotherapy for cancer treatment face serious challenges
such as drug resistance and toxic side effects. Complementary/Alternative medicine is …