During the last 30 years there have been many attempts to develop animal models of
obsessive-compulsive disorder (OCD). Most models have not been studied further following …

The great potential for NMDA receptor modulators as druggable targets in
neurodegenerative disorders has been met with limited success. Considered one of the rare …

Anxiety disorders are the most prevalent mental health conditions. Although they are less
visible than schizophrenia, depression, and bipolar disorder, they can be just as disabling …

Memantine is an N-methyl-d-aspartate receptor antagonist that is approved for the treatment
of moderate to severe Alzheimer's disease (AD). In this study, three groups of triple …

Background Increased physical exercise improves cognitive function and reduces pathology
associated with Alzheimer's disease (AD). However, the mechanisms underlying the …

The dysfunction and loss of basal forebrain cholinergic neurons and their cortical projections
are among the earliest pathological events in the pathogenesis of Alzheimer's disease (AD) …

N‐methyl‐d‐aspartate receptors (NMDARs) play a pivotal role in excitatory
neurotransmission, synaptic plasticity and brain development. Clinical and experimental …

Rationale Although pathological gambling (PG) is relatively common, pharmacotherapy
research for PG is limited. Memantine, an N-methyl d-aspartate receptor antagonist, appears …

Memantine is a moderate‐affinity, uncompetitive N‐methyl‐D‐aspartate (NMDA) receptor
antagonist that stabilizes cognitive, functional, and behavioral decline in patients with …

During the last 30 years there have been many attempts to develop animal models of
obsessive compulsive disorder (OCD), in the hope that they may provide a route for …