Pathogenesis underlying neurological manifestations of long COVID syndrome and potential therapeutics

A Leng, M Shah, SA Ahmad, L Premraj, K Wildi… - Cells, 2023 - mdpi.com
The development of long-term symptoms of coronavirus disease 2019 (COVID-19) more
than four weeks after primary infection, termed “long COVID” or post-acute sequela of …

The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

V Carlini, DM Noonan, E Abdalalem, D Goletti… - Frontiers in …, 2023 - frontiersin.org
Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …

Biomarkers in long COVID-19: A systematic review

YJ Lai, SH Liu, S Manachevakul, TA Lee… - Frontiers in …, 2023 - frontiersin.org
Purpose Long COVID, also known as post-acute sequelae of COVID-19, refers to the
constellation of long-term symptoms experienced by people suffering persistent symptoms …

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis

JX Yin, YL Agbana, ZS Sun, SW Fei, HQ Zhao… - Infectious Diseases of …, 2023 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) can involve persistence,
sequelae, and other clinical complications that last weeks to months to evolve into long …

[HTML][HTML] Long COVID: An inevitable sequela of SARS-CoV-2 infection

CC Lai, CK Hsu, MY Yen, PI Lee, WC Ko… - Journal of Microbiology …, 2023 - Elsevier
At present, there are more than 560 million confirmed cases of the coronavirus disease 2019
(COVID-19) worldwide. Although more than 98% of patients with severe acute respiratory …

The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of long COVID

J Li, Y Zhou, J Ma, Q Zhang, J Shao, S Liang… - … and Targeted Therapy, 2023 - nature.com
There have been hundreds of millions of cases of coronavirus disease 2019 (COVID-19),
which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With …

Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOVER initiative

H Bonilla, MJ Peluso, K Rodgers, JA Aberg… - Frontiers in …, 2023 - frontiersin.org
Although most individuals recover from acute SARS-CoV-2 infection, a significant number
continue to suffer from Post-Acute Sequelae of SARS-CoV-2 (PASC), including the …

Cellular and molecular biomarkers of long COVID: a scoping review

E Espín, C Yang, CP Shannon, S Assadian, D He… - …, 2023 - thelancet.com
Summary Background Long-COVID (LC) encompasses diverse symptoms lasting months
after the initial SARS-CoV-2 infection. Symptoms can be debilitating and affect the quality of …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

Pathophysiological mechanisms of thrombosis in acute and long COVID-19

H Jing, X Wu, M Xiang, L Liu, VA Novakovic… - Frontiers in …, 2022 - frontiersin.org
COVID-19 patients have a high incidence of thrombosis, and thromboembolic complications
are associated with severe COVID-19 and high mortality. COVID-19 disease is associated …