[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

[HTML][HTML] Current status of epidemiology, diagnosis, therapeutics, and vaccines for novel coronavirus disease 2019 (COVID-19)

DG Ahn, HJ Shin, MH Kim, S Lee, HS Kim… - … of microbiology and …, 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), which causes serious respiratory illness
such as pneumonia and lung failure, was first reported in Wuhan, the capital of Hubei …

[HTML][HTML] SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

W Sungnak, N Huang, C Bécavin, M Berg, R Queen… - Nature medicine, 2020 - nature.com
We investigated SARS-CoV-2 potential tropism by surveying expression of viral entry-
associated genes in single-cell RNA-sequencing data from multiple tissues from healthy …

Mechanism of thrombocytopenia in COVID-19 patients

P Xu, Q Zhou, J Xu - Annals of hematology, 2020 - Springer
Since December 2019, a novel coronavirus has spread throughout China and across the
world, causing a continuous increase in confirmed cases within a short period of time. Some …

SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis

A Bayati, R Kumar, V Francis, PS McPherson - Journal of Biological …, 2021 - ASBMB
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
COVID-19, so understanding its biology and infection mechanisms is critical to facing this …

The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells

M Hoffmann, H Kleine-Weber, N Krüger, M Müller… - BioRxiv, 2020 - biorxiv.org
The emergence of a novel, highly pathogenic coronavirus, 2019-nCoV, in China, and its
rapid national and international spread pose a global health emergency. Coronaviruses use …

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

CGK Ziegler, VN Miao, AH Owings, AW Navia, Y Tang… - Cell, 2021 - cell.com
SARS-CoV-2 infection can cause severe respiratory COVID-19. However, many individuals
present with isolated upper respiratory symptoms, suggesting potential to constrain viral …

Genetic screens identify host factors for SARS-CoV-2 and common cold coronaviruses

R Wang, CR Simoneau, J Kulsuptrakul, M Bouhaddou… - Cell, 2021 - cell.com
The Coronaviridae are a family of viruses that cause disease in humans ranging from mild
respiratory infection to potentially lethal acute respiratory distress syndrome. Finding host …

Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks

WM Schneider, JM Luna, HH Hoffmann… - Cell, 2021 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic has claimed the lives of
over one million people worldwide. The causative agent, severe acute respiratory syndrome …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a systemic infection

A Synowiec, A Szczepański… - Clinical microbiology …, 2021 - Am Soc Microbiol
To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …