There has been an escalation in reports over the last decade examining the efficacy of bone
marrow derived mesenchymal stem/stromal cells (BMSC) in bone tissue engineering and …

Effective regeneration of bone defects often presents significant challenges, particularly in
patients with decreased tissue regeneration capacity due to extensive trauma, disease …

In recent decades, mesenchymal stromal cells (MSCs) biomedical utilizing has attracted
worldwide growing attention. After the first report of the human MSCs obtaining from the …

Cell sheet technology has been widely used in bone tissue engineering and regenerative
medicine. However, controlling the shape and volume of large pieces of engineered bone …

Bone marrow stromal cells (BMSCs) and periosteum-derived cells (PDCs) represent
promising skeletal stem cell sources to treat critical-size bone defects. However, the large …

The most common clinical manifestations of age-related musculoskeletal degeneration are
osteoarthritis and osteoporosis, and these represent an enormous burden on modern …

A limited number of tissues can spontaneously regenerate following injury, and even fewer
can regenerate to a state comparable to mature, healthy adult tissue. Mesenchymal stem …

Stem cell-based therapy is a significant topic in regenerative medicine, with a predominant
role being played by human mesenchymal stem cells (hMSCs). The hMSCs have been …

Nonunions represent one of the major indications for clinical settings with stem cell‐based
therapies. The objective of this research was to systematically assess the current evidence …

Abstract Background Mesenchymal stem cells (MSCs) have alluring interest for clinical use
in orthopaedics based on their therapeutic potential through directed pluripotent …