[HTML][HTML] Cortico-striatal-thalamic loop circuits of the orbitofrontal cortex: promising therapeutic targets in psychiatric illness

P Fettes, L Schulze, J Downar - Frontiers in systems neuroscience, 2017 - frontiersin.org
Corticostriatal circuits through the orbitofrontal cortex (OFC) play key roles in complex
human behaviors such as evaluation, affect regulation and reward-based decision-making …

Early versus late onset obsessive–compulsive disorder: evidence for distinct subtypes

S Taylor - Clinical psychology review, 2011 - Elsevier
The distinction between early versus late onset is important for understanding many different
kinds of disorders. In an effort to identify etiologically homogeneous subtypes of obsessive …

Cortical abnormalities associated with pediatric and adult obsessive-compulsive disorder: findings from the ENIGMA Obsessive-Compulsive Disorder Working Group

PSW Boedhoe, L Schmaal, Y Abe… - American Journal of …, 2018 - Am Psychiatric Assoc
Objective: Brain imaging studies of structural abnormalities in OCD have yielded
inconsistent results, partly because of limited statistical power, clinical heterogeneity, and …

Meta-analytical comparison of voxel-based morphometry studies in obsessive-compulsive disorder vs other anxiety disorders

J Radua, OA van den Heuvel… - Archives of general …, 2010 - jamanetwork.com
Context Whether obsessive-compulsive disorder (OCD) is adequately classified as an
anxiety disorder is a matter of considerable debate. Objectives To quantitatively compare …

Comparative multimodal meta-analysis of structural and functional brain abnormalities in autism spectrum disorder and obsessive-compulsive disorder

CO Carlisi, LJ Norman, SS Lukito, J Radua… - Biological …, 2017 - Elsevier
Background Autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD)
share inhibitory control deficits possibly underlying poor control over stereotyped and …

Widespread structural brain changes in OCD: a systematic review of voxel-based morphometry studies

F Piras, F Piras, C Chiapponi, P Girardi, C Caltagirone… - Cortex, 2015 - Elsevier
The most widely accepted model of obsessive–compulsive disorder (OCD) assumes brain
abnormalities in the “affective circuit”, mainly consisting of volume reduction in the medial …

Meta-analytic investigations of structural grey matter, executive domain-related functional activations, and white matter diffusivity in obsessive compulsive disorder: an …

GK Eng, K Sim, SHA Chen - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
Obsessive–compulsive disorder (OCD) is a debilitating disorder. However, existing
neuroimaging findings involving executive function and structural abnormalities in OCD …

Morphometric correlation of impulsivity in medial prefrontal cortex

SS Cho, G Pellecchia, K Aminian, N Ray, B Segura… - Brain topography, 2013 - Springer
Impulsivity is a complex behaviour composed of different domains encompassing
behavioural dis-inhibition, risky decision-making and delay discounting abnormalities. To …

Abnormal spontaneous neural activity as a potential predictor of early treatment response in patients with obsessive–compulsive disorder

H Yan, X Shan, H Li, F Liu, W Guo - Journal of Affective Disorders, 2022 - Elsevier
Background We aimed to explore the value of early improvement in obsessive–compulsive
disorder (OCD) along with potential imaging changes after treatment with paroxetine in …

[HTML][HTML] Vestibular insights into cognition and psychiatry

C Gurvich, JJ Maller, B Lithgow, S Haghgooie… - Brain research, 2013 - Elsevier
The vestibular system has traditionally been thought of as a balance apparatus; however,
accumulating research suggests an association between vestibular function and psychiatric …