[HTML][HTML] Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup
Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …
strongly associated with adverse outcomes, including an increased risk of chronic kidney …
Current practice and evolving concepts in septic shock resuscitation
Clinical and pathophysiological understanding of septic shock has progressed exponentially
in the previous decades, translating into a steady decrease in septic shock-related morbidity …
in the previous decades, translating into a steady decrease in septic shock-related morbidity …
[HTML][HTML] Restriction of intravenous fluid in ICU patients with septic shock
TS Meyhoff, PB Hjortrup, J Wetterslev… - … England Journal of …, 2022 - Mass Medical Soc
Background Intravenous fluids are recommended for the treatment of patients who are in
septic shock, but higher fluid volumes have been associated with harm in patients who are …
septic shock, but higher fluid volumes have been associated with harm in patients who are …
[HTML][HTML] Balanced multielectrolyte solution versus saline in critically ill adults
Background Whether the use of balanced multielectrolyte solution (BMES) in preference to
0.9% sodium chloride solution (saline) in critically ill patients reduces the risk of acute kidney …
0.9% sodium chloride solution (saline) in critically ill patients reduces the risk of acute kidney …
Balanced crystalloids versus saline in critically ill adults—a systematic review with meta-analysis
Background The comparative efficacy and safety of balanced crystalloid solutions and saline
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …
Balanced crystalloid solution versus saline in deceased donor kidney transplantation (BEST-Fluids): a pragmatic, double-blind, randomised, controlled trial
Background Delayed graft function (DGF) is a major adverse complication of deceased
donor kidney transplantation. Intravenous fluids are routinely given to patients receiving a …
donor kidney transplantation. Intravenous fluids are routinely given to patients receiving a …
Adjustment for baseline characteristics in randomized clinical trials
MJ Holmberg, LW Andersen - JAMA, 2022 - jamanetwork.com
Thepurposeofrandomizationinclinicaltrialsis… are no systematic differences between
treatment groups with respect to measured and unmeasured baseline characteristics that …
treatment groups with respect to measured and unmeasured baseline characteristics that …
COVID-19 and acute kidney injury
In December 2019, a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
was discovered in Wuhan, China, the rapid spread of which culminated in a global …
was discovered in Wuhan, China, the rapid spread of which culminated in a global …
Effect of slower vs faster intravenous fluid bolus rates on mortality in critically ill patients: the basics randomized clinical trial
Importance Slower intravenous fluid infusion rates could reduce the formation of tissue
edema and organ dysfunction in critically ill patients; however, there are no data to support …
edema and organ dysfunction in critically ill patients; however, there are no data to support …
[HTML][HTML] The European guideline on management of major bleeding and coagulopathy following trauma
R Rossaint, A Afshari, B Bouillon, V Cerny… - Critical Care, 2023 - Springer
Background Severe trauma represents a major global public health burden and the
management of post-traumatic bleeding continues to challenge healthcare systems around …
management of post-traumatic bleeding continues to challenge healthcare systems around …