Immune checkpoint inhibitors associated cardiovascular immune-related adverse events

W Jo, T Won, A Daoud, D Čiháková - Frontiers in immunology, 2024 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are specialized monoclonal antibodies (mAbs) that
target immune checkpoints and their ligands, counteracting cancer cell-induced T-cell …

Mechanisms of T cell evasion by Epstein-Barr virus and implications for tumor survival

DG Sausen, MC Poirier, LM Spiers… - Frontiers in …, 2023 - frontiersin.org
Epstein-Barr virus (EBV) is a prevalent oncogenic virus estimated to infect greater than 90%
of the world's population. Following initial infection, it establishes latency in host B cells. EBV …

Efficacy and safety of cadonilimab in previously treated recurrent or metastatic nasopharyngeal carcinoma (COMPASSION-06): A phase II multicenter study

QY Chen, SS Guo, Y Luo, S Qu, DH Wu, XZ Chen… - Oral Oncology, 2024 - Elsevier
Objective This study was designed to assess the efficacy and safety of cadonilimab
monotherapy, a first-in-class, bi-specific PD-1/CTLA-4 antibody, in patients with previously …

Remodeling the tumor-immune microenvironment by anti-CTLA4 blockade enhanced subsequent anti-PD-1 efficacy in advanced nasopharyngeal carcinoma

Y Ma, H Zhou, F Luo, Y Zhang, C Zhu, W Li… - NPJ Precision …, 2024 - nature.com
Sequential immunotherapy has shown certain advantages in malignancy. Here, we aim to
evaluate the efficacy of sequential anti-CTLA-4 and anti-PD-1 treatment for recurrent or …

Facile manganese ion-coordination assembly of nanogels for synergistic cancer chemo–chemodynamic-immunotherapy

X Zhu, Q He, S He, X Li, X Huang, J Wang… - Chemical Engineering …, 2024 - Elsevier
Metal-ion therapy is an emerging technique for cancer treatment, where anticancer metals
trigger an immune response against tumor cells due to immunogenic cell death while …

Embracing Personalized Strategies in Radiotherapy for Nasopharyngeal Carcinoma: Beyond the Conventional Bounds of Fields and Borders

PL Yip, R You, MY Chen, MLK Chua - Cancers, 2024 - mdpi.com
Simple Summary In the dynamic landscape of nasopharyngeal carcinoma (NPC)
management, this review delves into a spectrum of radiotherapy (RT) practices, ranging from …

[PDF][PDF] 复发鼻咽癌的治疗: 挑战与希望并存

杨振东, 王仁生 - JOURNAL OF GUANGXI MEDICAL …, 2024 - journal.gxmu.edu.cn
摘要尽管随着以调强放疗为主的综合治疗的广泛开展, 鼻咽癌的复发率较传统二维放疗时代已经
明显降低, 但仍有相当一部分患者会在根治性放疗后出现复发. 复发鼻咽癌(rNPC) …

Combination of cadonilimab (anti-PD-1 and CTLA-4 bispecific antibody) with chemotherapy in anti-PD-1 resistant recurrent or metastatic nasopharyngeal carcinoma …

Y Xiang, YF Jiang, WX Bei, L Wang, N Lu, C Xu… - 2024 - researchsquare.com
Abstract Treatment options are limited for patients with recurrent or metastatic
nasopharyngeal carcinoma (RM-NPC) after failure to anti-PD-1 therapy. Cadonilimab …

EXPLORING NOVEL CELLULAR THERPEUTICS FOR IMMUNE CHECKPOINT INHIBITOR-ASSOCIATED MYOCARDITIS: INVESTIGATING TIGIT …

W Jo - 2024 - jscholarship.library.jhu.edu
Immune checkpoint inhibitors (ICIs) represent a promising class of monoclonal antibodies
designed to target immune checkpoints (ICs) and their ligands, thereby counteracting cancer …

A systematic review of antibody-drug conjugates and bispecific antibodies in head and neck squamous cell carcinoma and nasopharyngeal carcinoma: Charting the …

P Jiménez-Labaig, A Rullan, A Hernando-Calvo… - Cancer Treatment …, 2024 - Elsevier
Introduction There is a need to improve the outcomes of patients with head and neck
squamous cell carcinoma (HNSCC) and nasopharyngeal carcinoma (NPC), especially in …