Abstract CD4+ T helper (Th) cells are a crucial player in host defense but under certain
conditions can contribute to the pathogenesis of inflammatory and autoimmune diseases …

Human T-cell lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell
leukemia (ATL), an aggressive CD4+/CD25+ T-cell malignancy and of a severe …

This review focuses on three major aspects of oncoviruses' role in cancer development. To
begin, we discuss their geographic distribution, revealing that seven oncoviruses cause …

Viruses play an important role in the development of certain human cancers. They are
estimated to contribute 16% to all human cancers. Human T-cell leukemia virus type 1 …

MicroRNAs (miRNAs) can control cancer and cancer stem cells (CSCs), and this topic has
drawn immense attention recently. Stem cells are a tiny population of a bulk of tumor cells …

Human T-cell leukemia viruses type 1 (HTLV-1) and type 2 (HTLV-2) share a common
genome organization and expression strategy but have distinct pathological properties …

Human T‐cell lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic
paraparesis (HAM/TSP) disease is a chronic neuroinflammatory disease, which is …

Background Adult T-cell leukemia/lymphoma (ATLL) is a poor prognosis malignancy of
peripheral T-cells caused by human T-cell leukemia virus type 1 (HTLV-1). The low survival …

HTLV-1 infection causes a chronic progressive debilitating neuroinflammatory disease
which is called, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

Ceramide (Cer) is a bioactive cellular lipid with compartmentalized and tightly regulated
levels. Distinct metabolic pathways lead to the generation of Cer species with …