Pathogenic roles for Epstein–Barr virus (EBV) gene products in EBV-associated proliferative disorders
JM Middeldorp, AATP Brink, AJC Van den Brule… - Critical reviews in …, 2003 - Elsevier
Epstein–Barr virus (EBV) is associated with a still growing spectrum of clinical disorders,
ranging from acute and chronic inflammatory diseases to lymphoid and epithelial …
ranging from acute and chronic inflammatory diseases to lymphoid and epithelial …
The significance of LMP1 expression in nasopharyngeal carcinoma
SW Tsao, G Tramoutanis, CW Dawson, AKF Lo… - Seminars in cancer …, 2002 - Elsevier
The Epstein–Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) is a key effector of
EBV-mediated B cell transformation. LMP1 displays potent oncogenic properties in rodent …
EBV-mediated B cell transformation. LMP1 displays potent oncogenic properties in rodent …
Epstein-Barr virus latent membrane protein 1: structure and functions
HP Li, YS Chang - Journal of biomedical science, 2003 - karger.com
Abstract The Epstein-Barr virus latent membrane protein (LMP) 1 is a versatile protein that
has profound effects on target cells through its effect on constitutive cellular proteins, eg …
has profound effects on target cells through its effect on constitutive cellular proteins, eg …
Latent membrane protein 1 is critical for efficient growth transformation of human B cells by Epstein-Barr virus
U Dirmeier, B Neuhierl, E Kilger, G Reisbach… - Cancer Research, 2003 - AACR
The EBV latent membrane protein 1 (LMP1) is an integral membrane protein that acts like a
constitutively activated receptor. LMP1 interacts with members of the tumor necrosis factor …
constitutively activated receptor. LMP1 interacts with members of the tumor necrosis factor …
The latent membrane protein 1 oncogene modifies B-cell physiology by regulating autophagy
DY Lee, B Sugden - Oncogene, 2008 - nature.com
Epstein–Barr virus (EBV) is a herpes virus that is associated with several human cancers.
Infection of B cells by EBV leads to their induction and maintenance of proliferation and …
Infection of B cells by EBV leads to their induction and maintenance of proliferation and …
Nasopharyngeal carcinoma signaling pathway: an update on molecular biomarkers
W Tulalamba, T Janvilisri - International journal of cell biology, 2012 - Wiley Online Library
Nasopharyngeal carcinoma (NPC) is an uncommon cancer, which has a distinctive ethnic
and geographic distribution. Etiology of NPC is considered to be related with a complex …
and geographic distribution. Etiology of NPC is considered to be related with a complex …
[HTML][HTML] Leflunomide/teriflunomide inhibit Epstein-Barr virus (EBV)-induced lymphoproliferative disease and lytic viral replication
A Bilger, J Plowshay, S Ma, EA Barlow… - Oncotarget, 2017 - ncbi.nlm.nih.gov
EBV infection causes mononucleosis and is associated with specific subsets of B cell
lymphomas. Immunosuppressed patients such as organ transplant recipients are particularly …
lymphomas. Immunosuppressed patients such as organ transplant recipients are particularly …
CD40 and its viral mimic, LMP1: similar means to different ends
N Lam, B Sugden - Cellular signalling, 2003 - Elsevier
CD40 is an important regulator of diverse aspects of the immune response including the T-
cell-dependent humoral immune response, the development of antigen-presenting cells …
cell-dependent humoral immune response, the development of antigen-presenting cells …
The LMP1 oncogene of EBV activates PERK and the unfolded protein response to drive its own synthesis
DY Lee, B Sugden - Blood, The Journal of the American Society …, 2008 - ashpublications.org
The oncogene latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV) without a
ligand drives proliferation of EBV-infected B cells. Its levels vary in cells of clonal populations …
ligand drives proliferation of EBV-infected B cells. Its levels vary in cells of clonal populations …
Epstein–Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic …
M Higuchi, KM Izumi, E Kieff - Proceedings of the National …, 2001 - National Acad Sciences
Epstein–Barr virus encodes integral membrane proteins LMP1 and LMP2A in transformed
lymphoblastoid cell lines. We now find that LMP1 associates with the cell cytoskeleton …
lymphoblastoid cell lines. We now find that LMP1 associates with the cell cytoskeleton …