The human genetic code encrypted in thousands of genes holds the secret for synthesis of
proteins that drive all biological processes necessary for normal life and death. Though the …

Acetylcholinesterase is the physiological target for acute toxicity of nerve agents. Attempts to
protect acetylcholinesterase from phosphylation by nerve agents, is currently achieved by …

Recent years have seen an increasing number of incidence, in which organophosphate
nerve agents (OPNAs) have been used against civilians with devastating outcomes. Current …

Bioscavengers are an effective alternative approach for pre-and post-exposure treatments of
nerve agent (NA) poisoning. Bioscavengers are natural or recombinant enzymes, reactive …

The use of bioscavengers of organophosphorus agents (OPs) is the most effective
alternative approach for neutralization or detoxification of OPs for decontamination under …

This project assessed the effects of repeated low-dose exposure of guinea pigs to the
organophosphorus nerve agent sarin. Animals were injected once a day, 5 days per week …

In this study, we determined the ability of recombinant human liver prolidase to hydrolyze
nerve agents in vitro and its ability to afford protection in vivo in mice. Using adenovirus …

Background: Human prolidase has weak hydrolytic activity for toxic organophosphorus
compounds including diisopropyl fluorophosphates (DFP), chemical warfare nerve agents …

Sulfur mustard (Sm) or mustard gas [bis (2-chloroethyl) sulphide; CaSrn: 505-60-2] was first
synthesized by Despretz in 1822, and was rediscovered later by Guthrie and niemann. 1, 2 …

In recent years, toxic organophosphorus compounds (OPs) have been used for civilians,
becoming a great threat to the world. Alternative to the current treatment policy unpredictable …