Transcriptional regulation is essential for the correct functioning of cells during development
and in postnatal life. The basic Helix-loop-Helix (bHLH) superfamily of transcription factors is …

Antipsychotics represent the mainstay of schizophrenia pharmacological therapy, and their
role has been expanded in the last years to mood disorders treatment. Although introduced …

Major Depressive Disorder (MDD) represents a major global health concern, a body-mind
malady of rising prevalence worldwide nowadays. The complex network of mechanisms …

Multiple sclerosis (MS) is a chronic disease of the central nervous system that affects the
brain and spinal cord. There are several disease courses in MS including relapsing …

Background MicroRNAs (miRNAs) have been recently shown to exert several functional
roles in the development and function of neurons. Moreover, numerous miRNAs are present …

In this review, we examine the role of microRNAs in the development of the prefrontal cortex
(PFC) in adolescence and in individual differences in vulnerability to mental illness. We …

Exposure to stress can lead to long lasting behavioral and neurobiological consequences,
which may enhance the susceptibility for the onset of mental disorders. However, there are …

Subjects suffering from psychosis frequently experience anxiety. However, mechanisms
underlying this comorbidity remain still unclear. We investigated whether neurochemical and …

Abstract Major Depressive Disorder (MDD) is a severe and multifactorial psychiatric
condition. Evidence has shown that environmental factors, such as stress, significantly …

The clinical efficacy of lurasidone and quetiapine, two commonly prescribed atypical
antipsychotics for bipolar depression, has been inadequately studied in young patients. In …