Experience-dependent tuning of the olfactory system

N Pírez, M Klappenbach, FF Locatelli - Current Opinion in Insect Science, 2023 - Elsevier
Highlights•In the wild, perception of informative olfactory cues can be obscured by
concurrent odors.•Experience-dependent changes can tune detection and encoding of …

Postsynaptic plasticity of cholinergic synapses underlies the induction and expression of appetitive and familiarity memories in Drosophila

C Pribbenow, Y Chen, MM Heim, D Laber, S Reubold… - Elife, 2022 - elifesciences.org
In vertebrates, several forms of memory-relevant synaptic plasticity involve postsynaptic
rearrangements of glutamate receptors. In contrast, previous work indicates that Drosophila …

Learning and memory using Drosophila melanogaster: a focus on advances made in the fifth decade of research

RL Davis - Genetics, 2023 - academic.oup.com
In the last decade, researchers using Drosophila melanogaster have made extraordinary
progress in uncovering the mysteries underlying learning and memory. This progress has …

[HTML][HTML] Acetylcholine deficit causes dysfunctional inhibitory control in an aging-dependent manner

PR Sabandal, EB Saldes, KA Han - Scientific Reports, 2022 - nature.com
Inhibitory control is a key executive function that limits unnecessary thoughts and actions,
enabling an organism to appropriately execute goal-driven behaviors. The efficiency of this …

Neural circuit mechanisms for transforming learned olfactory valences into wind-oriented movement

Y Aso, D Yamada, D Bushey, KL Hibbard, M Sammons… - Elife, 2023 - elifesciences.org
How memories are used by the brain to guide future action is poorly understood. In olfactory
associative learning in Drosophila, multiple compartments of the mushroom body act in …

Associative learning drives longitudinally graded presynaptic plasticity of neurotransmitter release along axonal compartments

A Stahl, NC Noyes, T Boto, V Botero, CN Broyles… - Elife, 2022 - elifesciences.org
Anatomical and physiological compartmentalization of neurons is a mechanism to increase
the computational capacity of a circuit, and a major question is what role axonal …

[HTML][HTML] Visualization of learning-induced synaptic plasticity in output neurons of the Drosophila mushroom body γ-lobe

CE Hancock, V Rostami, EY Rachad, SH Deimel… - Scientific Reports, 2022 - nature.com
By learning, through experience, which stimuli coincide with dangers, it is possible to predict
outcomes and act pre-emptively to ensure survival. In insects, this process is localized to the …

Optogenetic and thermogenetic manipulation of defined neural circuits and behaviors in Drosophila

T Honda - Learning & Memory, 2022 - learnmem.cshlp.org
Neural network dynamics underlying flexible animal behaviors remain elusive. The fruit fly
Drosophila melanogaster is considered an excellent model in behavioral neuroscience …

Drosophila Reward Circuits

JS Hernandez, TM Brown, KR Kaun - Oxford Research Encyclopedia …, 2023 - oxfordre.com
The ability to sense and respond to a rewarding stimulus is a key advantage for animals in
their natural environment. The circuits that mediate these responses are complex, and it has …

Changing expectations: cognitive flexibility and reward processing in larval Drosophila

N Mancini - 2022 - repo.bibliothek.uni-halle.de
How brains function to generate appropriate behaviours is a key question for
neuroscientists. The larva of Drosophila melanogaster is emerging as a powerful study case …