Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

OSA is a heterogeneous disease with highly varying underlying mechanisms. OSA has
variable clinical manifestations with definable subsets having risk of particular …

Sleep apnea is caused by several endophenotypic traits, namely pharyngeal collapsibility,
poor muscle compensation, ventilatory instability (high loop gain), and arousability from …

Introduction The recent continuous positive airway pressure (CPAP) crisis has highlighted
the need for alternative obstructive sleep apnea (OSA) therapies. This article serves to …

Background The acute effect during positive pressure titration and long term efficacy of
acetazolamide (AZT) in high loop gain sleep apnea (HLGSA) is inadequately assessed. We …

The phenotyping of the pathophysiology of obstructive sleep apnoea (OSA) lies at the core
of tailored treatments and it is one of the most debated topics in sleep medicine research …

Background and objective Upper airway surgery for obstructive sleep apnoea (OSA) is an
alternative treatment for patients who are intolerant of continuous positive airway pressure …

Obstructive sleep apnea (OSA) is a severe sleep disorder associated with intermittent
hypoxia and sleep fragmentation. Cognitive impairment is a signifi-cant and common OSA …

Obstructive sleep apnea syndrome (OSA) is a multi-factorial disorder, with quite complex
endotypes, consisting of anatomical and non-anatomical pathophysiological factors …

Obstructive sleep apnoea (OSA) was traditionally thought to be mainly caused by obesity
and upper airway crowding, and hence OSA management was not personalised according …