Developmental origins of metabolic diseases

DJ Hoffman, TL Powell, ES Barrett… - Physiological …, 2021 - journals.physiology.org
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …

Environmental influences on the epigenome: exposure-associated DNA methylation in human populations

EM Martin, RC Fry - Annual review of public health, 2018 - annualreviews.org
DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

Endocrine disruptors acting on estrogen and androgen pathways cause reproductive disorders through multiple mechanisms: a review

S Amir, STA Shah, C Mamoulakis, AO Docea… - International Journal of …, 2021 - mdpi.com
Increasing contamination of the environment by toxic compounds such as endocrine
disrupting chemicals (EDCs) is one of the major causes of reproductive defects in both …

Plastics derived endocrine‐disrupting compounds and their effects on early development

S Basak, MK Das, AK Duttaroy - Birth defects research, 2020 - Wiley Online Library
Despite the fact that the estrogenic effects of bisphenols were first described 80 years ago,
recent data about its potential negative impact on birth outcome parameters raises a strong …

Endocrine disrupting chemical Bisphenol A and its potential effects on female health

IA Kawa, Q Fatima, SA Mir, H Jeelani… - Diabetes & Metabolic …, 2021 - Elsevier
Background and aim A large number of chemical compounds with endocrine-disrupting
activity have been documented. These chemicals are ubiquitous and widely used in many …

Praegnatio perturbatio—impact of endocrine-disrupting chemicals

V Padmanabhan, W Song… - Endocrine …, 2021 - academic.oup.com
The burden of adverse pregnancy outcomes such as preterm birth and low birth weight is
considerable across the world. Several risk factors for adverse pregnancy outcomes have …

Effects of prenatal exposure to endocrine disruptors and toxic metals on the fetal epigenome

PA Bommarito, E Martin, RC Fry - Epigenomics, 2017 - Taylor & Francis
Exposure to environmental contaminants during pregnancy has been linked to adverse
outcomes at birth and later in life. The link between prenatal exposures and latent health …

Prenatal epigenetics diets play protective roles against environmental pollution

S Li, M Chen, Y Li, TO Tollefsbol - Clinical epigenetics, 2019 - Springer
It is thought that germ cells and preimplantation embryos during development are most
susceptible to endogenous and exogenous environmental factors because the epigenome …

[HTML][HTML] Pregnancy-related maternal physiological adaptations and fetal chemical exposure

MT Vinnars, M Bixo, P Damdimopoulou - Molecular and Cellular …, 2023 - Elsevier
Prenatal life represents a susceptible window of development during which chemical
exposures can permanently alter fetal development, leading to an increased likelihood of …

The promises and challenges of toxico-epigenomics: environmental chemicals and their impacts on the epigenome

FFL Chung, Z Herceg - Environmental Health Perspectives, 2020 - ehp.niehs.nih.gov
Background: It has been estimated that a substantial portion of chronic and
noncommunicable diseases can be caused or exacerbated by exposure to environmental …