The present review aims to summarize the pharmacological profile of 1, 2, 4-triazole, one of
the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant …

Because of their medicinal characteristics, effectiveness, and importance, plant-derived
flavonoids have been a possible subject of research for many years, particularly in the last …

Abstract The 1, 2, 4-triazolo [1, 5-a] pyrimidine (TP) heterocycle, in spite of its relatively
simple structure, has proved to be remarkably versatile as evidenced by its use in many …

Alzheimer's disease (AD) is a non-recoverable progressive neurodegenerative disorder
most prevalent but not limited to the old age population. After all the scientific efforts, there …

Acetylcholinesterase (AChE) catalyzes the conversion of Aβ peptide to its aggregated form
and the peripheral anionic site (PAS) of AChE is mainly involved in this phenomenon. Also …

1, 3, 4-Oxadiazole, a five-membered aromatic ring can be seen in a number of synthetic
molecules. The peculiar structural feature of 1, 3, 4-oxadiazole ring with pyridine type of …

Alzheimer's disease (AD) is a progressive multifactorial neurodegenerative disorder.
Currently, no effective treatment is available and this is due to multiple factors involved in …

(piperazin-1-yl) single bond N-(1H-pyrazolo [3, 4-b] pyridin-3-yl) acetamides are described
as a new class of selective and potent acetylcholinesterase (AChE) inhibitors and amyloid β …

In our endeavor towards the development of potent multitarget ligands for the treatment of
Alzheimer's disease, a series of triazine-triazolopyrimidine hybrids were designed …

Abstract The [1, 2, 4] triazolo [1, 5-a] pyrimidines (TPs) comprise an important class of non-
naturally occurring small molecules that aroused the interest of researches. This scaffold is …