Undirected, homogeneous C–H bond functionalization: challenges and opportunities

JF Hartwig, MA Larsen - ACS central science, 2016 - ACS Publications
The functionalization of C–H bonds has created new approaches to preparing organic
molecules by enabling new strategic “disconnections” during the planning of a synthetic …

Direct (hetero) arylation polymerization: simplicity for conjugated polymer synthesis

JR Pouliot, F Grenier, JT Blaskovits, S Beaupré… - Chemical …, 2016 - ACS Publications
Direct (hetero) arylation polymerization (DHAP) has recently been established as an
environmentally benign method for the preparation of conjugated polymers. This synthetic …

Transition Metal Catalyzed Enantioselective C(sp2)–H Bond Functionalization

TK Achar, S Maiti, S Jana, D Maiti - ACS Catalysis, 2020 - ACS Publications
Direct catalytic transformation of C–H bonds to new functionalities has provided a powerful
strategy to synthesize complex molecular scaffolds in a straightforward way. Unstinting …

Cross-coupling and related reactions: connecting past success to the development of new reactions for the future

LC Campeau, N Hazari - Organometallics, 2018 - ACS Publications
Cross-coupling reactions, which were discovered almost 50 years ago, are widely used in
both industry and academia. Even though cross-coupling reactions now represent mature …

Buchwald-Hartwig reaction: an overview

MM Heravi, Z Kheilkordi, V Zadsirjan, M Heydari… - Journal of …, 2018 - Elsevier
Pd-catalyzed amination reaction of aryl halides has attracted much attention in recent years.
This review underscores selected important recent developments in the catalysis of one of …

Carboxylate-assisted transition-metal-catalyzed C− H bond functionalizations: mechanism and scope

L Ackermann - Chemical reviews, 2011 - ACS Publications
The site-selective formation of carbonrcarbon bonds through direct functionalizations of
otherwise unreactive carbonrhydrogen bonds constitutes an economically attractive strategy …

Occurrence, biogenesis, and synthesis of biologically active carbazole alkaloids

AW Schmidt, KR Reddy, HJ Knölker - Chemical reviews, 2012 - ACS Publications
Since our previous review, 1 there has been a tremendous development in the field of
carbazole alkaloids. New synthetic methodologies have been developed, existing …

Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation

L McMurray, F O'Hara, MJ Gaunt - Chemical Society Reviews, 2011 - pubs.rsc.org
Metal-catalysed C–H bond functionalisation has had a significant impact on how chemists
make molecules. Translating the methodological developments to their use in the assembly …

Transition‐metal‐catalyzed direct arylation of (hetero) arenes by C H bond cleavage

L Ackermann, R Vicente… - Angewandte Chemie …, 2009 - Wiley Online Library
The area of transition‐metal‐catalyzed direct arylation through cleavage of C H bonds has
undergone rapid development in recent years, and is becoming an increasingly viable …

Beyond Directing Groups: Transition‐Metal‐Catalyzed C H Activation of Simple Arenes

N Kuhl, MN Hopkinson… - Angewandte Chemie …, 2012 - Wiley Online Library
The use of coordinating moieties as directing groups for the functionalization of aromatic C
H bonds has become an established tool to enhance reactivity and induce regioselectivity …